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XBB.1.5 Kraken cracked: Gibbs energies of binding and biosynthesis of the XBB.1.5 variant of SARS-CoV-2

Authorized Users Only
2023
Authors
Popović, Marko
Article (Published version)
,
Elsevier
Metadata
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Abstract
The SARS-CoV-2 Hydra with many heads (variants) has been causing the COVID-19 pandemic for 3 years. The appearance of every new head (SARS-CoV-2 variant) causes a new pandemic wave. The last in the series is the XBB.1.5 “Kraken” variant. In the general public (social media) and in the scientific community (scientific journals), during the last several weeks since the variant has appeared, the question was raised of whether the infectivity of the new variant will be greater. This article attempts to provide the answer. Analysis of thermodynamic driving forces of binding and biosynthesis leads to the conclusion that infectivity of the XBB.1.5 variant could be increased to a certain extent. The pathogenicity of the XBB.1.5 variant seems to be unchanged compared to the other Omicron variants.
Keywords:
Omicron variant / Infectivity / Pathogenicity / Biothermodynamics / COVID-19 / Viral evolution
Source:
Microbiological Research, 2023, 270, 127337-
Publisher:
  • Elsevier

DOI: 10.1016/j.micres.2023.127337

ISSN: 0944-5013

PubMed: 36804126

Scopus: 2-s2.0-85148332405
[ Google Scholar ]
2
URI
https://cer.ihtm.bg.ac.rs/handle/123456789/6050
Collections
  • Radovi istraživača pre dolaska u IHTM / Researchers' papers before joining ICTM
Institution/Community
IHTM
TY  - JOUR
AU  - Popović, Marko
PY  - 2023
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/6050
AB  - The SARS-CoV-2 Hydra with many heads (variants) has been causing the COVID-19 pandemic for 3 years. The appearance of every new head (SARS-CoV-2 variant) causes a new pandemic wave. The last in the series is the XBB.1.5 “Kraken” variant. In the general public (social media) and in the scientific community (scientific journals), during the last several weeks since the variant has appeared, the question was raised of whether the infectivity of the new variant will be greater. This article attempts to provide the answer. Analysis of thermodynamic driving forces of binding and biosynthesis leads to the conclusion that infectivity of the XBB.1.5 variant could be increased to a certain extent. The pathogenicity of the XBB.1.5 variant seems to be unchanged compared to the other Omicron variants.
PB  - Elsevier
T2  - Microbiological Research
T1  - XBB.1.5 Kraken cracked: Gibbs energies of binding and biosynthesis of the XBB.1.5 variant of SARS-CoV-2
VL  - 270
SP  - 127337
DO  - 10.1016/j.micres.2023.127337
ER  - 
@article{
author = "Popović, Marko",
year = "2023",
abstract = "The SARS-CoV-2 Hydra with many heads (variants) has been causing the COVID-19 pandemic for 3 years. The appearance of every new head (SARS-CoV-2 variant) causes a new pandemic wave. The last in the series is the XBB.1.5 “Kraken” variant. In the general public (social media) and in the scientific community (scientific journals), during the last several weeks since the variant has appeared, the question was raised of whether the infectivity of the new variant will be greater. This article attempts to provide the answer. Analysis of thermodynamic driving forces of binding and biosynthesis leads to the conclusion that infectivity of the XBB.1.5 variant could be increased to a certain extent. The pathogenicity of the XBB.1.5 variant seems to be unchanged compared to the other Omicron variants.",
publisher = "Elsevier",
journal = "Microbiological Research",
title = "XBB.1.5 Kraken cracked: Gibbs energies of binding and biosynthesis of the XBB.1.5 variant of SARS-CoV-2",
volume = "270",
pages = "127337",
doi = "10.1016/j.micres.2023.127337"
}
Popović, M.. (2023). XBB.1.5 Kraken cracked: Gibbs energies of binding and biosynthesis of the XBB.1.5 variant of SARS-CoV-2. in Microbiological Research
Elsevier., 270, 127337.
https://doi.org/10.1016/j.micres.2023.127337
Popović M. XBB.1.5 Kraken cracked: Gibbs energies of binding and biosynthesis of the XBB.1.5 variant of SARS-CoV-2. in Microbiological Research. 2023;270:127337.
doi:10.1016/j.micres.2023.127337 .
Popović, Marko, "XBB.1.5 Kraken cracked: Gibbs energies of binding and biosynthesis of the XBB.1.5 variant of SARS-CoV-2" in Microbiological Research, 270 (2023):127337,
https://doi.org/10.1016/j.micres.2023.127337 . .

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