Hydride reduction of B-norcholestane 5α,6α-epoxide
Hidridna redukcija B-norholestan 5α,6α-epoksida
Abstract
B-Norcholestane epoxide 2 is reduced with lithium aluminium hydride to give either the 3β,6α-diol 3 or the corresponding 3β,5α-diol 4, depending on the quality of the reducing reagent employed. Aplausible mechanistic explanation of the obtained results is suggested.
Redukcijom B-norholestan-epoksida 2 pomoću litijum-aluminijum-hidrida dobijeni su odgovarajući 3β,6α-diol 3 ili 3β,5α-diol 4, u zavisnosti od kvaliteta upotrebljenog redukcionog reagensa. Predloženo je verovatno mehanističko tumačenje dobijenih rezultata.
Keywords:
5α,6α-epoxy-B-norcholestan-3β-yl acetate / 5α-hydroxy-B-norcholestan-3β-yl acetate / 6α-hydroxy-B-nor-5β-cholestan-3β-yl acetate / lithium aluminium hydride / lithium triethylborohydrideSource:
Journal of the Serbian Chemical Society, 2002, 67, 2, 69-75Publisher:
- Serbian Chemical Society
Projects:
- Project MESTD
DOI: 10.2298/JSC0202069B
ISSN: 0352-5139