Triterpene composition of the plant species Euphorbia palustris

Abstract

Plant species of the genus Euphorbia have an important place in the traditional medicine due to the secondary metabolites which they produce. The most important metabolites come from the classes of diterpenes and triterpenes. The studies have shown that these compounds can have antitumour, antiviral, antibacterial, anti-inflammatory and other properties. The aim of the research was to investigatethe triterpene composition of Euphorbia palustris. Using chromatographic techniques, four triterpene derivatives were isolated from the plant material, as follows: (+)-tirucallol (1), lanosterol (2), 27-nor-3βhydroxycycloart-23-en-25-one (3) and (+)-obtusifoliol (4). In the continuation of the research, their biological activities will be examined.

Biljne vrste roda Euphorbia imaju važno mesto u tradicionalnoj medicini zahvaljujući sekundarnim metabolitima koje proizvode. Najznačajniji metaboliti pripadaju klasama diterpena i triterpena. Istraživanja su pokazala da ova jedinjenja imaju antitumorska, antivirusna, antibakterijska, antiinflamatorna i druga svojstva. Cilj ovog istraživanja bio je ispitivanje triterpenskog sastava biljne vrste Euphorbia palustris. Primenom hromatografskih tehnika iz biljnog materijala izolovana su četiri triterpenska derivata i to:(+)-tirukalol (1), lanosterol (2), 27-nor-3β-hidroksicikloart-23-en-25-on (3) i (+)- obtusifoliol (4). U nastavku istraživanja biće ispitane njihove biološke aktivnosti.