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Structure-activity relationship, docking analysis and ADME properties of newly designed, potent serotonin 5HT1a receptor ligands

dc.creatorJevtić, Ivana
dc.creatorAndrić, Deana
dc.creatorPenjišević, Jelena
dc.creatorŠukalović, Vladimir
dc.creatorDukic-Stefanovic, Sladjana
dc.creatorKostić-Rajačić, Slađana
dc.date.accessioned2023-02-28T13:06:52Z
dc.date.available2023-02-28T13:06:52Z
dc.date.issued2022
dc.identifier.urihttps://cer.ihtm.bg.ac.rs/handle/123456789/5851
dc.description.abstractSerotonin 5HT1a receptors belongs to a class G-protein coupled receptors and it is widely recognized as one of the targets for treating neurological disorders such depression and schizophrenia. N-arylpiperazine structural motif is present in many compounds with pronounced 5HT1a activity including recently approved aripiprazole for the treatment of the major depressive disorder.sr
dc.language.isoensr
dc.publisherEuropean Federation for Medicinal chemistry and Chemical biology (EFMC)sr
dc.relationinfo:eu-repo/grantAgreement/MESTD/inst-2020/200026/RS//sr
dc.relationinfo:eu-repo/grantAgreement/MESTD/inst-2020/200168/RS//sr
dc.rightsrestrictedAccesssr
dc.sourceBook of abstracts - EFMC-YMCS-Young Medicinal Chemists' Symposium, September 8-9, 2022, Nice, Francesr
dc.subjectSerotonin-1A receptorsr
dc.subjectADMEsr
dc.titleStructure-activity relationship, docking analysis and ADME properties of newly designed, potent serotonin 5HT1a receptor ligandssr
dc.typeconferenceObjectsr
dc.rights.licenseARRsr
dc.citation.spage66
dc.citation.epage66
dc.identifier.rcubhttps://hdl.handle.net/21.15107/rcub_cer_5851
dc.type.versionpublishedVersionsr


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