Thermoplastic polyurethanes containing poly(dimethylsiloxane): Synthesis, properties and biocompatibility
Конференцијски прилог (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Thermoplastic polyurethane (TPU) materials containing poly(dimethylsiloxane) (PDMS) segments have been used in various medical devices, primarily because of their good mechanical properties and biostability. However, PDMS-based TPUs, currently utilized for biomedical applications, have sub-optimal biocompatibility in terms of resistance to cell adhesion and relatively poor support for endothelial cell growth, which diminishes their efficacy. In order to significantly improve and extend clinical applications of PDMS-based TPUs, the aim of the research was to enhance the endothelial cell attachment and blood-contacting properties of these materials [1,2]. This study is focused on overview of the synthesis, characterization of the structure, surface, thermal, and mechanical properties, as well as investigation of biocompatibility of PDMS-based TPUs. The synthesized PDMS based TPUs exhibit good surface and thermo-mechanical properties, as well as good biocompatibility equal to current comm...ercial biomedical TPUs.
Кључне речи:
polyurethane / properties / biocompatibilityИзвор:
Book of Abstracts - 4th Conference of Young Chemists of Serbia, November 5, 2016, Belgrade, Serbia, 2016, 3-3Издавач:
- Serbian Chemical Society
Финансирање / пројекти:
Институција/група
IHTMTY - CONF AU - Pergal, Marija PY - 2016 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/5826 AB - Thermoplastic polyurethane (TPU) materials containing poly(dimethylsiloxane) (PDMS) segments have been used in various medical devices, primarily because of their good mechanical properties and biostability. However, PDMS-based TPUs, currently utilized for biomedical applications, have sub-optimal biocompatibility in terms of resistance to cell adhesion and relatively poor support for endothelial cell growth, which diminishes their efficacy. In order to significantly improve and extend clinical applications of PDMS-based TPUs, the aim of the research was to enhance the endothelial cell attachment and blood-contacting properties of these materials [1,2]. This study is focused on overview of the synthesis, characterization of the structure, surface, thermal, and mechanical properties, as well as investigation of biocompatibility of PDMS-based TPUs. The synthesized PDMS based TPUs exhibit good surface and thermo-mechanical properties, as well as good biocompatibility equal to current commercial biomedical TPUs. PB - Serbian Chemical Society C3 - Book of Abstracts - 4th Conference of Young Chemists of Serbia, November 5, 2016, Belgrade, Serbia T1 - Thermoplastic polyurethanes containing poly(dimethylsiloxane): Synthesis, properties and biocompatibility SP - 3 EP - 3 UR - https://hdl.handle.net/21.15107/rcub_cer_5826 ER -
@conference{ author = "Pergal, Marija", year = "2016", abstract = "Thermoplastic polyurethane (TPU) materials containing poly(dimethylsiloxane) (PDMS) segments have been used in various medical devices, primarily because of their good mechanical properties and biostability. However, PDMS-based TPUs, currently utilized for biomedical applications, have sub-optimal biocompatibility in terms of resistance to cell adhesion and relatively poor support for endothelial cell growth, which diminishes their efficacy. In order to significantly improve and extend clinical applications of PDMS-based TPUs, the aim of the research was to enhance the endothelial cell attachment and blood-contacting properties of these materials [1,2]. This study is focused on overview of the synthesis, characterization of the structure, surface, thermal, and mechanical properties, as well as investigation of biocompatibility of PDMS-based TPUs. The synthesized PDMS based TPUs exhibit good surface and thermo-mechanical properties, as well as good biocompatibility equal to current commercial biomedical TPUs.", publisher = "Serbian Chemical Society", journal = "Book of Abstracts - 4th Conference of Young Chemists of Serbia, November 5, 2016, Belgrade, Serbia", title = "Thermoplastic polyurethanes containing poly(dimethylsiloxane): Synthesis, properties and biocompatibility", pages = "3-3", url = "https://hdl.handle.net/21.15107/rcub_cer_5826" }
Pergal, M.. (2016). Thermoplastic polyurethanes containing poly(dimethylsiloxane): Synthesis, properties and biocompatibility. in Book of Abstracts - 4th Conference of Young Chemists of Serbia, November 5, 2016, Belgrade, Serbia Serbian Chemical Society., 3-3. https://hdl.handle.net/21.15107/rcub_cer_5826
Pergal M. Thermoplastic polyurethanes containing poly(dimethylsiloxane): Synthesis, properties and biocompatibility. in Book of Abstracts - 4th Conference of Young Chemists of Serbia, November 5, 2016, Belgrade, Serbia. 2016;:3-3. https://hdl.handle.net/21.15107/rcub_cer_5826 .
Pergal, Marija, "Thermoplastic polyurethanes containing poly(dimethylsiloxane): Synthesis, properties and biocompatibility" in Book of Abstracts - 4th Conference of Young Chemists of Serbia, November 5, 2016, Belgrade, Serbia (2016):3-3, https://hdl.handle.net/21.15107/rcub_cer_5826 .