Redox properties of one hydrophobic spin probe 3-(acetoxymethoxy)carbonyl-2,2,5,5-tetramethyl pyrrolidine-N-oxyl (AM-CxP) and corresponding water-soluble compound, 3-carboxy-2,2,5,5-
tetramethyl-pyrrolidine-N-oxyl (3-CxP) were evaluated using electrochemical and EPR methods. The
electrochemical behavior of two spin probes was investigated by cyclic voltammetry in phosphate
buffer solution. The voltammograms of both compounds exhibited a single redox couple related to
nitroxyl radical. EPR spectroscopy revealed that 3-CxP is less susceptible to reduction by Ascorbate
than AM-CxP, nevertheless, both spin probes exhibit a great potential for in vivo applications
TY - CONF
AU - Pavićević, Aleksandra
AU - Peyrot, Fabien
AU - Mojović, Zorica
AU - Mojović, Miloš
PY - 2022
UR - https://cer.ihtm.bg.ac.rs/handle/123456789/5550
AB - Redox properties of one hydrophobic spin probe 3-(acetoxymethoxy)carbonyl-2,2,5,5-tetramethyl pyrrolidine-N-oxyl (AM-CxP) and corresponding water-soluble compound, 3-carboxy-2,2,5,5-
tetramethyl-pyrrolidine-N-oxyl (3-CxP) were evaluated using electrochemical and EPR methods. The
electrochemical behavior of two spin probes was investigated by cyclic voltammetry in phosphate
buffer solution. The voltammograms of both compounds exhibited a single redox couple related to
nitroxyl radical. EPR spectroscopy revealed that 3-CxP is less susceptible to reduction by Ascorbate
than AM-CxP, nevertheless, both spin probes exhibit a great potential for in vivo applications
PB - Društvo fizikohemičara Srbije
C3 - Proceedings - 16th International Conference on fundamental and applied aspects of Physical chemistry
T1 - Electrochemical and EPR investigation of spin probes acetoxymethoxycarbonyl- and carboxy-proxyl
VL - 1
SP - 225
EP - 228
UR - https://hdl.handle.net/21.15107/rcub_cer_5550
ER -
@conference{
author = "Pavićević, Aleksandra and Peyrot, Fabien and Mojović, Zorica and Mojović, Miloš",
year = "2022",
abstract = "Redox properties of one hydrophobic spin probe 3-(acetoxymethoxy)carbonyl-2,2,5,5-tetramethyl pyrrolidine-N-oxyl (AM-CxP) and corresponding water-soluble compound, 3-carboxy-2,2,5,5-
tetramethyl-pyrrolidine-N-oxyl (3-CxP) were evaluated using electrochemical and EPR methods. The
electrochemical behavior of two spin probes was investigated by cyclic voltammetry in phosphate
buffer solution. The voltammograms of both compounds exhibited a single redox couple related to
nitroxyl radical. EPR spectroscopy revealed that 3-CxP is less susceptible to reduction by Ascorbate
than AM-CxP, nevertheless, both spin probes exhibit a great potential for in vivo applications",
publisher = "Društvo fizikohemičara Srbije",
journal = "Proceedings - 16th International Conference on fundamental and applied aspects of Physical chemistry",
title = "Electrochemical and EPR investigation of spin probes acetoxymethoxycarbonyl- and carboxy-proxyl",
volume = "1",
pages = "225-228",
url = "https://hdl.handle.net/21.15107/rcub_cer_5550"
}
Pavićević, A., Peyrot, F., Mojović, Z.,& Mojović, M.. (2022). Electrochemical and EPR investigation of spin probes acetoxymethoxycarbonyl- and carboxy-proxyl. in Proceedings - 16th International Conference on fundamental and applied aspects of Physical chemistry
Društvo fizikohemičara Srbije., 1, 225-228.
https://hdl.handle.net/21.15107/rcub_cer_5550
Pavićević A, Peyrot F, Mojović Z, Mojović M. Electrochemical and EPR investigation of spin probes acetoxymethoxycarbonyl- and carboxy-proxyl. in Proceedings - 16th International Conference on fundamental and applied aspects of Physical chemistry. 2022;1:225-228.
https://hdl.handle.net/21.15107/rcub_cer_5550 .
Pavićević, Aleksandra, Peyrot, Fabien, Mojović, Zorica, Mojović, Miloš, "Electrochemical and EPR investigation of spin probes acetoxymethoxycarbonyl- and carboxy-proxyl" in Proceedings - 16th International Conference on fundamental and applied aspects of Physical chemistry, 1 (2022):225-228,
https://hdl.handle.net/21.15107/rcub_cer_5550 .
