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1,2-Dithioles
dc.creator | Rašović, Aleksandar | |
dc.date.accessioned | 2023-01-02T12:23:10Z | |
dc.date.available | 2023-01-02T12:23:10Z | |
dc.date.issued | 2022 | |
dc.identifier.isbn | 978-0-12-818656-5 | |
dc.identifier.uri | https://cer.ihtm.bg.ac.rs/handle/123456789/5514 | |
dc.description.abstract | Advances, during the period 2008–18, in the chemistry of 1,2-dithioles as well as their applications in medicine and technology are presented. Additionally, for the better understanding of the extent of recent progress as well as a more complete overview of the topics, the chapter also includes a critical summary of the most relevant previously reported work concerning this subject. The examples of the synthesis of different 1,2-dithioles, starting from various fragments, are described herein following a systematic classification. Their reactivity is also thoroughly reviewed. The significance of lipoic acid, which has been also called a “universal antioxidant,” in the development of the multitarget profile drugs against Alzheimer's disease (AD) and its application for the preparation of functionalized nanoparticles is summarized. A survey of the literature data on the theoretical and experimental study of antioxidant properties of LA as well as its biochemistry is presented. The natural occurrence of compounds containing 1,2-dithioles is reviewed. Novel X-ray determinations of structures containing 1,2-dithiole moiety are listed. The synthesis and structure characterization of 3,3aλ4,4-trithia-1-azapentalenes is thoroughly discussed. | sr |
dc.language.iso | en | sr |
dc.publisher | Elsevier | sr |
dc.relation | info:eu-repo/grantAgreement/MESTD/inst-2020/200026/RS// | sr |
dc.rights | restrictedAccess | sr |
dc.source | Comprehensive Heterocyclic Chemistry IV | sr |
dc.subject | 1,2-Dithiolanes | sr |
dc.subject | 1,2-Dithiole-3-thiones | sr |
dc.subject | 1,2-Dithioles | sr |
dc.subject | 1,2-Dithiolium salts | sr |
dc.subject | 3,3aλ4,4-Trithia-1-azapentalenes | sr |
dc.subject | Antioxidant | sr |
dc.subject | Biochemistry | sr |
dc.subject | Biological activity | sr |
dc.subject | Leinamycin | sr |
dc.subject | Lipoic acid (LA) | sr |
dc.subject | Nanotechnology | sr |
dc.subject | Structure | sr |
dc.subject | synthesis and reactivity | sr |
dc.subject | X-ray crystallography | sr |
dc.subject | Naturally occurring | sr |
dc.title | 1,2-Dithioles | sr |
dc.type | bookPart | sr |
dc.rights.license | ARR | sr |
dc.citation.volume | 4 | |
dc.citation.spage | 766 | |
dc.citation.epage | 833 | |
dc.citation.rank | M13 | |
dc.identifier.doi | 10.1016/B978-0-12-818655-8.00137-2 | |
dc.identifier.scopus | 2-s2.0-85143554266 | |
dc.type.version | publishedVersion | sr |