Tocopherols, early described as a vitamin that brings birth, have been identified as redox compounds capable of radical scavenging in a lipid phase. The recent finding that alpha-tocopherol phosphate is present in cells in small amounts assigned alpha-tocopherol to the
group of signaling molecules, rather than to that of antioxidants. When antioxidant levels are augmented by either genetic or pharmacologic means the impact on tumor cells both in vitro and in
vivo has been to inhibit tumor growth and/or differentiation. We examined effect of alpha-tocopherol addition on free thiol content and SOD activity in K562 cells.
Keywords:
Tocopherols / human erythroleukemia / oxidative stress / CuZnSOD
Source:
New Biotechnology, 2009, 25 supplement, S5-
Publisher:
Elsevier
Note:
Abstracts of the 14th European Congress on Biotechnology (ECB 14)-Symbiosis, Barcelona, Spain, 13-16 September
TY - CONF
AU - Spasić, Snežana
AU - Bogdanović, V.
AU - Martinov, Olga B.
AU - Miletić, Srđan
AU - Vrvić, Miroslav
PY - 2009
UR - https://cer.ihtm.bg.ac.rs/handle/123456789/5132
AB - Tocopherols, early described as a vitamin that brings birth, have been identified as redox compounds capable of radical scavenging in a lipid phase. The recent finding that alpha-tocopherol phosphate is present in cells in small amounts assigned alpha-tocopherol to the
group of signaling molecules, rather than to that of antioxidants. When antioxidant levels are augmented by either genetic or pharmacologic means the impact on tumor cells both in vitro and in
vivo has been to inhibit tumor growth and/or differentiation. We examined effect of alpha-tocopherol addition on free thiol content and SOD activity in K562 cells.
PB - Elsevier
C3 - New Biotechnology
T1 - Redox status of K562 cells after α-tocopherol treatment
VL - 25 supplement
SP - S5
DO - 10.1016/j.nbt.2009.06.015
ER -
@conference{
author = "Spasić, Snežana and Bogdanović, V. and Martinov, Olga B. and Miletić, Srđan and Vrvić, Miroslav",
year = "2009",
abstract = "Tocopherols, early described as a vitamin that brings birth, have been identified as redox compounds capable of radical scavenging in a lipid phase. The recent finding that alpha-tocopherol phosphate is present in cells in small amounts assigned alpha-tocopherol to the
group of signaling molecules, rather than to that of antioxidants. When antioxidant levels are augmented by either genetic or pharmacologic means the impact on tumor cells both in vitro and in
vivo has been to inhibit tumor growth and/or differentiation. We examined effect of alpha-tocopherol addition on free thiol content and SOD activity in K562 cells.",
publisher = "Elsevier",
journal = "New Biotechnology",
title = "Redox status of K562 cells after α-tocopherol treatment",
volume = "25 supplement",
pages = "S5",
doi = "10.1016/j.nbt.2009.06.015"
}
Spasić, S., Bogdanović, V., Martinov, O. B., Miletić, S.,& Vrvić, M.. (2009). Redox status of K562 cells after α-tocopherol treatment. in New Biotechnology
Elsevier., 25 supplement, S5.
https://doi.org/10.1016/j.nbt.2009.06.015
Spasić S, Bogdanović V, Martinov OB, Miletić S, Vrvić M. Redox status of K562 cells after α-tocopherol treatment. in New Biotechnology. 2009;25 supplement:S5.
doi:10.1016/j.nbt.2009.06.015 .
Spasić, Snežana, Bogdanović, V., Martinov, Olga B., Miletić, Srđan, Vrvić, Miroslav, "Redox status of K562 cells after α-tocopherol treatment" in New Biotechnology, 25 supplement (2009):S5,
https://doi.org/10.1016/j.nbt.2009.06.015 . .
