Thin-layer chromatography in bioassays of antimicrobial compounds from plants
Само за регистроване кориснике
2021
Аутори
Šegan, SandraŽivković-Radovanović, Vukosava
Tosti, Tomislav
Ristivojević, Petar
Milojković-Opsenica, Dušanka
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Growing antibiotic resistance creates a need to find new antimicrobial agents characterized by diverse chemical structures and pharmaceutical activity. The higher plants synthesize many specialized metabolites as a part of their normal metabolic activity and have been extensively used for centuries in treatment of different diseases. They have a wide activity range depending on the species, topography and climate, and may have different categories of active principles. In contrast to conventional antimicrobial techniques, planar chromatography in combination with biological detection can be an appropriate method of choice for fast, simple, and low-cost screening of plant extract for successful detection of antimicrobial agents which can be good candidates for lead compounds. To date, all bioautography steps such as chromatographic separation, detection with bacteria cells, incubation, and visualization of bioactive bands were improved and optimized. This review gives an overview of bio...autography procedure from extraction to structure elucidation of antimicrobial compounds from plants.
Кључне речи:
Antimicrobial detection / extraction / HPTLC / plant sources / structure elucidationИзвор:
Journal of Liquid Chromatography & Related Technologies, 2021Издавач:
- USA :Taylor & Francis INC
Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200026 (Универзитет у Београду, Институт за хемију, технологију и металургију - ИХТМ) (RS-MESTD-inst-2020-200026)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200168 (Универзитет у Београду, Хемијски факултет) (RS-MESTD-inst-2020-200168)
DOI: 10.1080/10826076.2021.1968429
ISSN: 1082-6076
WoS: 000690315600001
Scopus: 2-s2.0-85113700242
Институција/група
IHTMTY - JOUR AU - Šegan, Sandra AU - Živković-Radovanović, Vukosava AU - Tosti, Tomislav AU - Ristivojević, Petar AU - Milojković-Opsenica, Dušanka PY - 2021 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/4770 AB - Growing antibiotic resistance creates a need to find new antimicrobial agents characterized by diverse chemical structures and pharmaceutical activity. The higher plants synthesize many specialized metabolites as a part of their normal metabolic activity and have been extensively used for centuries in treatment of different diseases. They have a wide activity range depending on the species, topography and climate, and may have different categories of active principles. In contrast to conventional antimicrobial techniques, planar chromatography in combination with biological detection can be an appropriate method of choice for fast, simple, and low-cost screening of plant extract for successful detection of antimicrobial agents which can be good candidates for lead compounds. To date, all bioautography steps such as chromatographic separation, detection with bacteria cells, incubation, and visualization of bioactive bands were improved and optimized. This review gives an overview of bioautography procedure from extraction to structure elucidation of antimicrobial compounds from plants. PB - USA :Taylor & Francis INC T2 - Journal of Liquid Chromatography & Related Technologies T1 - Thin-layer chromatography in bioassays of antimicrobial compounds from plants DO - 10.1080/10826076.2021.1968429 ER -
@article{ author = "Šegan, Sandra and Živković-Radovanović, Vukosava and Tosti, Tomislav and Ristivojević, Petar and Milojković-Opsenica, Dušanka", year = "2021", abstract = "Growing antibiotic resistance creates a need to find new antimicrobial agents characterized by diverse chemical structures and pharmaceutical activity. The higher plants synthesize many specialized metabolites as a part of their normal metabolic activity and have been extensively used for centuries in treatment of different diseases. They have a wide activity range depending on the species, topography and climate, and may have different categories of active principles. In contrast to conventional antimicrobial techniques, planar chromatography in combination with biological detection can be an appropriate method of choice for fast, simple, and low-cost screening of plant extract for successful detection of antimicrobial agents which can be good candidates for lead compounds. To date, all bioautography steps such as chromatographic separation, detection with bacteria cells, incubation, and visualization of bioactive bands were improved and optimized. This review gives an overview of bioautography procedure from extraction to structure elucidation of antimicrobial compounds from plants.", publisher = "USA :Taylor & Francis INC", journal = "Journal of Liquid Chromatography & Related Technologies", title = "Thin-layer chromatography in bioassays of antimicrobial compounds from plants", doi = "10.1080/10826076.2021.1968429" }
Šegan, S., Živković-Radovanović, V., Tosti, T., Ristivojević, P.,& Milojković-Opsenica, D.. (2021). Thin-layer chromatography in bioassays of antimicrobial compounds from plants. in Journal of Liquid Chromatography & Related Technologies USA :Taylor & Francis INC.. https://doi.org/10.1080/10826076.2021.1968429
Šegan S, Živković-Radovanović V, Tosti T, Ristivojević P, Milojković-Opsenica D. Thin-layer chromatography in bioassays of antimicrobial compounds from plants. in Journal of Liquid Chromatography & Related Technologies. 2021;. doi:10.1080/10826076.2021.1968429 .
Šegan, Sandra, Živković-Radovanović, Vukosava, Tosti, Tomislav, Ristivojević, Petar, Milojković-Opsenica, Dušanka, "Thin-layer chromatography in bioassays of antimicrobial compounds from plants" in Journal of Liquid Chromatography & Related Technologies (2021), https://doi.org/10.1080/10826076.2021.1968429 . .