The effects of supplementation with selenous yeast and ionizing radiation on selenium (Se) content and distribution were evaluated in rat tissues (liver, kidney, spleen, heart, muscle, blood, front brain, hind brain, hypothalamus, pituitary, adrenal glands, testes, and hair). This study had 16 Se-supplemented (0.5 μg Se/d) and 16 placebo adult male Wistar rats. One half of the animals (eight Se-supplemented and eight placebos) were irradiated with a single dose of 4.2 Gy from a Co-60 source and sacrificed 7 d after irradiation along with nonirradiated animals and analyzed for Se content determination. The data obtained showed that selenous yeast supplementation increased Se levels in rat tissues (highest increases in hypothalamus, 161%; hind brain, 126%; spleen, 110%; and adrenal gland, 105%). Ionizing radiation induced significant changes in Se content and distribution (decrease in liver, blood, hair, femoral muscle, spleen, and hypothalamus; increase in kidney, testes, adrenal glands..., and brain of placebo group). Supplementation with selenous yeast reduces changes in Se content and distribution after irradiation. It seems that the animal tissue susceptibility to oxidative damage may be correlated to their ability to retain Se in tissues.
Keywords:
ionizing radiation / rats / Selenous yeast / tissue Se
Source:
Biological Trace Element Research, 1992, 33, 1-3, 197-204
Publisher:
Heidelberg : Springer
Funding / projects:
The Serbian Academy of Sciences and Arts, Project F. 51
TY - JOUR
AU - Đujić, Ivana
AU - Jozanov-Stankov, Olga
AU - Mandić, Miodrag
AU - Demajo, Miroslav
AU - Vrvić, Miroslav
PY - 1992
UR - https://cer.ihtm.bg.ac.rs/handle/123456789/4741
AB - The effects of supplementation with selenous yeast and ionizing radiation on selenium (Se) content and distribution were evaluated in rat tissues (liver, kidney, spleen, heart, muscle, blood, front brain, hind brain, hypothalamus, pituitary, adrenal glands, testes, and hair). This study had 16 Se-supplemented (0.5 μg Se/d) and 16 placebo adult male Wistar rats. One half of the animals (eight Se-supplemented and eight placebos) were irradiated with a single dose of 4.2 Gy from a Co-60 source and sacrificed 7 d after irradiation along with nonirradiated animals and analyzed for Se content determination. The data obtained showed that selenous yeast supplementation increased Se levels in rat tissues (highest increases in hypothalamus, 161%; hind brain, 126%; spleen, 110%; and adrenal gland, 105%). Ionizing radiation induced significant changes in Se content and distribution (decrease in liver, blood, hair, femoral muscle, spleen, and hypothalamus; increase in kidney, testes, adrenal glands, and brain of placebo group). Supplementation with selenous yeast reduces changes in Se content and distribution after irradiation. It seems that the animal tissue susceptibility to oxidative damage may be correlated to their ability to retain Se in tissues.
PB - Heidelberg : Springer
T2 - Biological Trace Element Research
T1 - Selenium content and distribution in rat tissues irradiated with gamma rays
VL - 33
IS - 1-3
SP - 197
EP - 204
DO - 10.1007/BF02784023
ER -
@article{
author = "Đujić, Ivana and Jozanov-Stankov, Olga and Mandić, Miodrag and Demajo, Miroslav and Vrvić, Miroslav",
year = "1992",
abstract = "The effects of supplementation with selenous yeast and ionizing radiation on selenium (Se) content and distribution were evaluated in rat tissues (liver, kidney, spleen, heart, muscle, blood, front brain, hind brain, hypothalamus, pituitary, adrenal glands, testes, and hair). This study had 16 Se-supplemented (0.5 μg Se/d) and 16 placebo adult male Wistar rats. One half of the animals (eight Se-supplemented and eight placebos) were irradiated with a single dose of 4.2 Gy from a Co-60 source and sacrificed 7 d after irradiation along with nonirradiated animals and analyzed for Se content determination. The data obtained showed that selenous yeast supplementation increased Se levels in rat tissues (highest increases in hypothalamus, 161%; hind brain, 126%; spleen, 110%; and adrenal gland, 105%). Ionizing radiation induced significant changes in Se content and distribution (decrease in liver, blood, hair, femoral muscle, spleen, and hypothalamus; increase in kidney, testes, adrenal glands, and brain of placebo group). Supplementation with selenous yeast reduces changes in Se content and distribution after irradiation. It seems that the animal tissue susceptibility to oxidative damage may be correlated to their ability to retain Se in tissues.",
publisher = "Heidelberg : Springer",
journal = "Biological Trace Element Research",
title = "Selenium content and distribution in rat tissues irradiated with gamma rays",
volume = "33",
number = "1-3",
pages = "197-204",
doi = "10.1007/BF02784023"
}
Đujić, I., Jozanov-Stankov, O., Mandić, M., Demajo, M.,& Vrvić, M.. (1992). Selenium content and distribution in rat tissues irradiated with gamma rays. in Biological Trace Element Research
Heidelberg : Springer., 33(1-3), 197-204.
https://doi.org/10.1007/BF02784023
Đujić I, Jozanov-Stankov O, Mandić M, Demajo M, Vrvić M. Selenium content and distribution in rat tissues irradiated with gamma rays. in Biological Trace Element Research. 1992;33(1-3):197-204.
doi:10.1007/BF02784023 .
Đujić, Ivana, Jozanov-Stankov, Olga, Mandić, Miodrag, Demajo, Miroslav, Vrvić, Miroslav, "Selenium content and distribution in rat tissues irradiated with gamma rays" in Biological Trace Element Research, 33, no. 1-3 (1992):197-204,
https://doi.org/10.1007/BF02784023 . .
, 