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dc.creatorMilenković, Ivana
dc.creatorRadotić, Ksenija
dc.creatorDespotović, Jovana
dc.creatorLončarević, Branka
dc.creatorLješević, Marija
dc.creatorSpasić, Slađana Z.
dc.creatorNikolić, Aleksandra
dc.creatorBeškoski, Vladimir P.
dc.date.accessioned2021-06-08T12:47:07Z
dc.date.available2021-06-08T12:47:07Z
dc.date.issued2021
dc.identifier.issn0166-445X
dc.identifier.urihttps://cer.ihtm.bg.ac.rs/handle/123456789/4687
dc.description.abstractCerium oxide nanoparticles (nCeO2) have widespread applications, but they can be hazardous to the environment. Some reports indicate the toxic effect of nCeO2 on tested animals, but literature data are mainly contradictory. Coating of nCeO2 can improve their suspension stability and change their interaction with the environment, which can consequently decrease their toxic effects. Herein, the exopolysaccharides levan and pullulan, due to their high water solubility, biocompatibility, and ability to form film, were used to coat nCeO2. Additionally, the monosaccharide glucose was used, since it is a common material for nanoparticle coating. This is the first study investigating the impact of carbohydrate-coated nCeO2 in comparison to uncoated nCeO2 using different model organisms. The aim of this study was to test the acute toxicity of carbohydrate-coated nCeO2 on the bacterium Vibrio fischeri NRRL B-11177, the crustacean Daphnia magna, and zebrafish Danio rerio. The second aim was to investigate the effects of nCeO2 on respiration in Daphnia magna which was performed for the first time. Finally, it was important to see the relation between Ce bioaccumulation in Daphnia magna and Danio rerio and other investigated parameters. Our results revealed that the coating decreased the toxicity of nCeO2 on Vibrio fischeri. The coating of nCeO2 did not affect the nanoparticles’ accumulation/adsorption or mortality in Daphnia magna or Danio rerio. Monitoring of respiration in Daphnia magna revealed changes in CO2 production after exposure to coated nCeO2, while the crustacean's O2 consumption was not affected by any of the coated nCeO2. In summary, this study revealed that, at 200 mg L−1, uncoated and carbohydrate-coated nCeO2 are not toxic for the tested organisms, however, the CO2 production in Daphnia magna is different when they are treated with coated and uncoated nCeO2. The highest production was in glucose and levan-coated nCeO2 according to their highest suspension stability.sr
dc.language.isoensr
dc.publisherElseviersr
dc.relationinfo:eu-repo/grantAgreement/MESTD/inst-2020/200042/RS//sr
dc.relationinfo:eu-repo/grantAgreement/MESTD/inst-2020/200053/RS//sr
dc.relationinfo:eu-repo/grantAgreement/MESTD/inst-2020/200026/RS//sr
dc.relationinfo:eu-repo/grantAgreement/MESTD/inst-2020/200168/RS//sr
dc.relation.isversionofhttps://cer.ihtm.bg.ac.rs/handle/123456789/4689
dc.rightsrestrictedAccesssr
dc.sourceAquatic Toxicologysr
dc.subjectVibrio fischerisr
dc.subjectCeO2sr
dc.subjectCoatingsr
dc.subjectDaphnia magnasr
dc.subjectDanio reriosr
dc.subjectNanoparticlessr
dc.titleToxicity investigation of CeO2 nanoparticles coated with glucose and exopolysaccharides levan and pullulan on the bacterium Vibrio fischeri and aquatic organisms Daphnia magna and Danio reriosr
dc.typearticlesr
dc.rights.licenseARRsr
dcterms.abstractСпасић, Слађана З.; Лончаревић, Бранка; Деспотовић, Јована; Радотић, Ксенија; Миленковић, Ивана; Бешкоски, Владимир П.; Николић, Aлександра; Љешевић, Марија;
dc.citation.volume236
dc.citation.spage105867
dc.citation.rankaM21~
dc.description.otherThe peer-reviewed version: [https://cer.ihtm.bg.ac.rs/handle/123456789/4689]
dc.identifier.pmid34052720
dc.identifier.doi10.1016/j.aquatox.2021.105867
dc.type.versionpublishedVersionsr


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