Carboxylated single-wall carbon nanotubes decorated with SiO2 coated-Nd2O3 nanoparticles as an electrochemical sensor for L-DOPA detection
Само за регистроване кориснике
2021
Аутори
Đurđić, SlađanaStanković, Vesna
Vlahović, Filip
Ognjanović, Miloš
Kalcher, Kurt
Manojlović, Dragan
Mutić, Jelena
Stanković, Dalibor M.
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
L-DOPA (L-3,4-dihydroxyphenylalanine), the precursor of dopamine, is widely used in the treatment of Parkinson’s disease, thus determining and monitoring the concentration of L-DOPA is of utmost importance for both medical and scientific purposes. Although many analytical approaches, designed for drug detection and quantification, already exist, there is a constant need for modification of old and tailoring of new, faster, and selective methods. Redox active chemical species, such as L-DOPA, can be measured directly by electrochemical means, whereas electrochemical sensors combine sensitivity and selectivity within a small analytical device. This work demonstrates the development of such electrochemical sensor, based on carboxylated single-wall carbon nanotubes (SWCNT-COOH) decorated with SiO2 coated-Nd2O3 nanoparticles, and further application for the detection of L-DOPA. Developed SWCNT-COOH@Nd2O3-SiO2 sensor shows linear response in the range from 2 µmol L−1 to 52 µmol L−1 analyte c...oncentration, and beside the low detection limit, it is characterized by a fast response time, as well as good life-time, reproducibility and repeatability.
Кључне речи:
Electrochemical sensing / L-DOPA / Nanostructure / SWCNT-COOH@Nd2O3-SiO2Извор:
Microchemical Journal, 2021, 168, 106416-Издавач:
- Elsevier
Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200168 (Универзитет у Београду, Хемијски факултет) (RS-MESTD-inst-2020-200168)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200026 (Универзитет у Београду, Институт за хемију, технологију и металургију - ИХТМ) (RS-MESTD-inst-2020-200026)
- CEEPUS network CIII-CZ-0212-13-1920-M-131892
DOI: 10.1016/j.microc.2021.106416
ISSN: 0026-265X
WoS: 000675852600014
Scopus: 2-s2.0-85106605961
Институција/група
IHTMTY - JOUR AU - Đurđić, Slađana AU - Stanković, Vesna AU - Vlahović, Filip AU - Ognjanović, Miloš AU - Kalcher, Kurt AU - Manojlović, Dragan AU - Mutić, Jelena AU - Stanković, Dalibor M. PY - 2021 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/4683 AB - L-DOPA (L-3,4-dihydroxyphenylalanine), the precursor of dopamine, is widely used in the treatment of Parkinson’s disease, thus determining and monitoring the concentration of L-DOPA is of utmost importance for both medical and scientific purposes. Although many analytical approaches, designed for drug detection and quantification, already exist, there is a constant need for modification of old and tailoring of new, faster, and selective methods. Redox active chemical species, such as L-DOPA, can be measured directly by electrochemical means, whereas electrochemical sensors combine sensitivity and selectivity within a small analytical device. This work demonstrates the development of such electrochemical sensor, based on carboxylated single-wall carbon nanotubes (SWCNT-COOH) decorated with SiO2 coated-Nd2O3 nanoparticles, and further application for the detection of L-DOPA. Developed SWCNT-COOH@Nd2O3-SiO2 sensor shows linear response in the range from 2 µmol L−1 to 52 µmol L−1 analyte concentration, and beside the low detection limit, it is characterized by a fast response time, as well as good life-time, reproducibility and repeatability. PB - Elsevier T2 - Microchemical Journal T1 - Carboxylated single-wall carbon nanotubes decorated with SiO2 coated-Nd2O3 nanoparticles as an electrochemical sensor for L-DOPA detection VL - 168 SP - 106416 DO - 10.1016/j.microc.2021.106416 ER -
@article{ author = "Đurđić, Slađana and Stanković, Vesna and Vlahović, Filip and Ognjanović, Miloš and Kalcher, Kurt and Manojlović, Dragan and Mutić, Jelena and Stanković, Dalibor M.", year = "2021", abstract = "L-DOPA (L-3,4-dihydroxyphenylalanine), the precursor of dopamine, is widely used in the treatment of Parkinson’s disease, thus determining and monitoring the concentration of L-DOPA is of utmost importance for both medical and scientific purposes. Although many analytical approaches, designed for drug detection and quantification, already exist, there is a constant need for modification of old and tailoring of new, faster, and selective methods. Redox active chemical species, such as L-DOPA, can be measured directly by electrochemical means, whereas electrochemical sensors combine sensitivity and selectivity within a small analytical device. This work demonstrates the development of such electrochemical sensor, based on carboxylated single-wall carbon nanotubes (SWCNT-COOH) decorated with SiO2 coated-Nd2O3 nanoparticles, and further application for the detection of L-DOPA. Developed SWCNT-COOH@Nd2O3-SiO2 sensor shows linear response in the range from 2 µmol L−1 to 52 µmol L−1 analyte concentration, and beside the low detection limit, it is characterized by a fast response time, as well as good life-time, reproducibility and repeatability.", publisher = "Elsevier", journal = "Microchemical Journal", title = "Carboxylated single-wall carbon nanotubes decorated with SiO2 coated-Nd2O3 nanoparticles as an electrochemical sensor for L-DOPA detection", volume = "168", pages = "106416", doi = "10.1016/j.microc.2021.106416" }
Đurđić, S., Stanković, V., Vlahović, F., Ognjanović, M., Kalcher, K., Manojlović, D., Mutić, J.,& Stanković, D. M.. (2021). Carboxylated single-wall carbon nanotubes decorated with SiO2 coated-Nd2O3 nanoparticles as an electrochemical sensor for L-DOPA detection. in Microchemical Journal Elsevier., 168, 106416. https://doi.org/10.1016/j.microc.2021.106416
Đurđić S, Stanković V, Vlahović F, Ognjanović M, Kalcher K, Manojlović D, Mutić J, Stanković DM. Carboxylated single-wall carbon nanotubes decorated with SiO2 coated-Nd2O3 nanoparticles as an electrochemical sensor for L-DOPA detection. in Microchemical Journal. 2021;168:106416. doi:10.1016/j.microc.2021.106416 .
Đurđić, Slađana, Stanković, Vesna, Vlahović, Filip, Ognjanović, Miloš, Kalcher, Kurt, Manojlović, Dragan, Mutić, Jelena, Stanković, Dalibor M., "Carboxylated single-wall carbon nanotubes decorated with SiO2 coated-Nd2O3 nanoparticles as an electrochemical sensor for L-DOPA detection" in Microchemical Journal, 168 (2021):106416, https://doi.org/10.1016/j.microc.2021.106416 . .