Visible light promoted photoredox C(sp3)-H bond functionalization of tetrahydroisoquinolines in flow
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2021
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
A merger of organocatalysis and visible light photoredox catalysis performed in flow allowed access to a wide range of functionalizedN-aryl-substituted tetrahydroisoquinolines (THIQs) in a formal C-H oxidation/Mannich reaction. Strecker type functionalization and copper-catalyzed alkynylation of severalN-aryl-substituted THIQs were also successfully performed in flow, giving valuable products with high efficiencies. The use of custom-made porous polymeric type microreactors proved to be crucial regarding the C-H oxidation step and overall reaction performance.
Ključne reči:
Light / Catalysis / Alkynylations / Copper catalyzed / Functionalizations / Micro reactor / Organocatalysis / Overall reactions / Photoredox catalysis / TetrahydroisoquinolinesIzvor:
Organic and Biomolecular Chemistry, 2021, 19, 12, 2668-2675Izdavač:
- Royal Society of Chemistry
Finansiranje / projekti:
- Ministarstvo nauke, tehnološkog razvoja i inovacija Republike Srbije, institucionalno finansiranje - 200026 (Univerzitet u Beogradu, Institut za hemiju, tehnologiju i metalurgiju - IHTM) (RS-MESTD-inst-2020-200026)
- The Proof of Concept project of Innovation Fund of Republic of Serbia no. 5183.
Napomena:
- Supplementary material: https://cer.ihtm.bg.ac.rs/handle/123456789/4495
Povezane informacije:
- Povezani sadržaj
https://cer.ihtm.bg.ac.rs/handle/123456789/4495
DOI: 10.1039/d0ob02582h
ISSN: 1477-0520
PubMed: 33666639
WoS: 000635741400006
Scopus: 2-s2.0-85103475295
Institucija/grupa
IHTMTY - JOUR AU - Filipović, Ana AU - Džambaski, Zdravko AU - Vasiljević-Radović, Dana AU - Bondžić, Bojan PY - 2021 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/4494 AB - A merger of organocatalysis and visible light photoredox catalysis performed in flow allowed access to a wide range of functionalizedN-aryl-substituted tetrahydroisoquinolines (THIQs) in a formal C-H oxidation/Mannich reaction. Strecker type functionalization and copper-catalyzed alkynylation of severalN-aryl-substituted THIQs were also successfully performed in flow, giving valuable products with high efficiencies. The use of custom-made porous polymeric type microreactors proved to be crucial regarding the C-H oxidation step and overall reaction performance. PB - Royal Society of Chemistry T2 - Organic and Biomolecular Chemistry T1 - Visible light promoted photoredox C(sp3)-H bond functionalization of tetrahydroisoquinolines in flow VL - 19 IS - 12 SP - 2668 EP - 2675 DO - 10.1039/d0ob02582h ER -
@article{ author = "Filipović, Ana and Džambaski, Zdravko and Vasiljević-Radović, Dana and Bondžić, Bojan", year = "2021", abstract = "A merger of organocatalysis and visible light photoredox catalysis performed in flow allowed access to a wide range of functionalizedN-aryl-substituted tetrahydroisoquinolines (THIQs) in a formal C-H oxidation/Mannich reaction. Strecker type functionalization and copper-catalyzed alkynylation of severalN-aryl-substituted THIQs were also successfully performed in flow, giving valuable products with high efficiencies. The use of custom-made porous polymeric type microreactors proved to be crucial regarding the C-H oxidation step and overall reaction performance.", publisher = "Royal Society of Chemistry", journal = "Organic and Biomolecular Chemistry", title = "Visible light promoted photoredox C(sp3)-H bond functionalization of tetrahydroisoquinolines in flow", volume = "19", number = "12", pages = "2668-2675", doi = "10.1039/d0ob02582h" }
Filipović, A., Džambaski, Z., Vasiljević-Radović, D.,& Bondžić, B.. (2021). Visible light promoted photoredox C(sp3)-H bond functionalization of tetrahydroisoquinolines in flow. in Organic and Biomolecular Chemistry Royal Society of Chemistry., 19(12), 2668-2675. https://doi.org/10.1039/d0ob02582h
Filipović A, Džambaski Z, Vasiljević-Radović D, Bondžić B. Visible light promoted photoredox C(sp3)-H bond functionalization of tetrahydroisoquinolines in flow. in Organic and Biomolecular Chemistry. 2021;19(12):2668-2675. doi:10.1039/d0ob02582h .
Filipović, Ana, Džambaski, Zdravko, Vasiljević-Radović, Dana, Bondžić, Bojan, "Visible light promoted photoredox C(sp3)-H bond functionalization of tetrahydroisoquinolines in flow" in Organic and Biomolecular Chemistry, 19, no. 12 (2021):2668-2675, https://doi.org/10.1039/d0ob02582h . .