CER - Central Repository
Institute of Chemistry, Technology and Metallurgy
    • English
    • Српски
    • Српски (Serbia)
  • English 
    • English
    • Serbian (Cyrillic)
    • Serbian (Latin)
  • Login
View Item 
  •   CER
  • IHTM
  • Radovi istraživača / Researchers' publications
  • View Item
  •   CER
  • IHTM
  • Radovi istraživača / Researchers' publications
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Synthesis and evaluation of several cathechol bioisosteres as potential dopamine receptor ligands

Authorized Users Only
1991
Authors
Kostić, Slađana
Šoškić, Vukić
Joksimović, Jelena
Article (Published version)
Metadata
Show full item record
Abstract
Derivatives of benzimidazole (I), benzimidazolone (II), benzimidazolethione (III), 2,3-dihydroxyquinoxaline (IV) and the noncyclic acetamide (V) and t rifluoroacetamide (VI) of the corresponding 1,2-pheny-lenediamiane were synthesized and tested for DA-ergic activity. III and IV had a moderate affini ty for the D2 receptors of the bovine caudate nucleus. Several potential DA-receptor ligands were synthesized. III and IV expressed the affinity for the D-2 receptor.
Keywords:
dopamine / drug synthesis / drug receptor binding / D-2 receptor
Source:
Bioorganic and Medicinal Chemistry Letters, 1991, 1, 8, 403-406
Publisher:
  • Elsevier
Funding / projects:
  • The Research Science Funds of Serbia, Grant No. 8016.

DOI: 10.1016/S0960-894X(00)80265-6

ISSN: 0960-894X; 1464-3405

Scopus: 2-s2.0-0026002989
[ Google Scholar ]
8
URI
https://cer.ihtm.bg.ac.rs/handle/123456789/4384
Collections
  • Radovi istraživača / Researchers' publications
Institution/Community
IHTM
TY  - JOUR
AU  - Kostić, Slađana
AU  - Šoškić, Vukić
AU  - Joksimović, Jelena
PY  - 1991
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4384
AB  - Derivatives of benzimidazole (I), benzimidazolone (II), benzimidazolethione (III), 2,3-dihydroxyquinoxaline (IV) and the noncyclic acetamide (V) and t rifluoroacetamide (VI) of the corresponding 1,2-pheny-lenediamiane were synthesized and tested for DA-ergic activity. III and IV had a moderate affini ty for the D2 receptors of the bovine caudate nucleus. Several potential DA-receptor ligands were synthesized. III and IV expressed the affinity for the D-2 receptor.
PB  - Elsevier
T2  - Bioorganic and Medicinal Chemistry Letters
T1  - Synthesis and evaluation of several cathechol bioisosteres as potential dopamine receptor ligands
VL  - 1
IS  - 8
SP  - 403
EP  - 406
DO  - 10.1016/S0960-894X(00)80265-6
ER  - 
@article{
author = "Kostić, Slađana and Šoškić, Vukić and Joksimović, Jelena",
year = "1991",
abstract = "Derivatives of benzimidazole (I), benzimidazolone (II), benzimidazolethione (III), 2,3-dihydroxyquinoxaline (IV) and the noncyclic acetamide (V) and t rifluoroacetamide (VI) of the corresponding 1,2-pheny-lenediamiane were synthesized and tested for DA-ergic activity. III and IV had a moderate affini ty for the D2 receptors of the bovine caudate nucleus. Several potential DA-receptor ligands were synthesized. III and IV expressed the affinity for the D-2 receptor.",
publisher = "Elsevier",
journal = "Bioorganic and Medicinal Chemistry Letters",
title = "Synthesis and evaluation of several cathechol bioisosteres as potential dopamine receptor ligands",
volume = "1",
number = "8",
pages = "403-406",
doi = "10.1016/S0960-894X(00)80265-6"
}
Kostić, S., Šoškić, V.,& Joksimović, J.. (1991). Synthesis and evaluation of several cathechol bioisosteres as potential dopamine receptor ligands. in Bioorganic and Medicinal Chemistry Letters
Elsevier., 1(8), 403-406.
https://doi.org/10.1016/S0960-894X(00)80265-6
Kostić S, Šoškić V, Joksimović J. Synthesis and evaluation of several cathechol bioisosteres as potential dopamine receptor ligands. in Bioorganic and Medicinal Chemistry Letters. 1991;1(8):403-406.
doi:10.1016/S0960-894X(00)80265-6 .
Kostić, Slađana, Šoškić, Vukić, Joksimović, Jelena, "Synthesis and evaluation of several cathechol bioisosteres as potential dopamine receptor ligands" in Bioorganic and Medicinal Chemistry Letters, 1, no. 8 (1991):403-406,
https://doi.org/10.1016/S0960-894X(00)80265-6 . .

DSpace software copyright © 2002-2015  DuraSpace
About CeR – Central Repository | Send Feedback

re3dataOpenAIRERCUB
 

 

All of DSpaceInstitutions/communitiesAuthorsTitlesSubjectsThis institutionAuthorsTitlesSubjects

Statistics

View Usage Statistics

DSpace software copyright © 2002-2015  DuraSpace
About CeR – Central Repository | Send Feedback

re3dataOpenAIRERCUB