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Covalent modification of hexokinase by biologically active quinones

Authorized Users Only
2005
Authors
Božić, Tatjana T.
Novaković, Irena
Gašić, Miroslav J.
Sladić, Dušan
Conference object (Published version)
Metadata
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Abstract
In this work, inhibition of sulfhydryl containing glycolytic enzyme hexokinase by avarone and its derivatives was studied. The enzyme contains lysine and sulfhydryl residues, which can be modified by the quinone moiety. Our results show that avarone and its derivatives are capable of covalent modification of hexokinase.
Keywords:
antitumor agents / quinone / hexokinase / phosphofructokinase / oxygen radicals / avarone
Source:
FEBS Journal / Federation of European of Biochemical Societies, 2005, 272, 302-302
Publisher:
  • Oxford : Blackwell Publishing

ISSN: 1742-464X

WoS: 000234826101550

[ Google Scholar ]
Handle
https://hdl.handle.net/21.15107/rcub_cherry_752
URI
https://cer.ihtm.bg.ac.rs/handle/123456789/4171
Collections
  • Radovi istraživača / Researchers' publications
Institution/Community
IHTM
TY  - CONF
AU  - Božić, Tatjana T.
AU  - Novaković, Irena
AU  - Gašić, Miroslav J.
AU  - Sladić, Dušan
PY  - 2005
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/4171
AB  - In this work, inhibition of sulfhydryl containing glycolytic enzyme hexokinase by avarone and its derivatives was studied. The enzyme contains lysine and sulfhydryl residues, which can be modified by the quinone moiety. Our results show that avarone and its derivatives are capable of covalent modification of hexokinase.
PB  - Oxford : Blackwell Publishing
C3  - FEBS Journal / Federation of European of Biochemical Societies
T1  - Covalent modification of hexokinase by biologically active quinones
VL  - 272
SP  - 302
EP  - 302
UR  - https://hdl.handle.net/21.15107/rcub_cherry_752
ER  - 
@conference{
author = "Božić, Tatjana T. and Novaković, Irena and Gašić, Miroslav J. and Sladić, Dušan",
year = "2005",
abstract = "In this work, inhibition of sulfhydryl containing glycolytic enzyme hexokinase by avarone and its derivatives was studied. The enzyme contains lysine and sulfhydryl residues, which can be modified by the quinone moiety. Our results show that avarone and its derivatives are capable of covalent modification of hexokinase.",
publisher = "Oxford : Blackwell Publishing",
journal = "FEBS Journal / Federation of European of Biochemical Societies",
title = "Covalent modification of hexokinase by biologically active quinones",
volume = "272",
pages = "302-302",
url = "https://hdl.handle.net/21.15107/rcub_cherry_752"
}
Božić, T. T., Novaković, I., Gašić, M. J.,& Sladić, D.. (2005). Covalent modification of hexokinase by biologically active quinones. in FEBS Journal / Federation of European of Biochemical Societies
Oxford : Blackwell Publishing., 272, 302-302.
https://hdl.handle.net/21.15107/rcub_cherry_752
Božić TT, Novaković I, Gašić MJ, Sladić D. Covalent modification of hexokinase by biologically active quinones. in FEBS Journal / Federation of European of Biochemical Societies. 2005;272:302-302.
https://hdl.handle.net/21.15107/rcub_cherry_752 .
Božić, Tatjana T., Novaković, Irena, Gašić, Miroslav J., Sladić, Dušan, "Covalent modification of hexokinase by biologically active quinones" in FEBS Journal / Federation of European of Biochemical Societies, 272 (2005):302-302,
https://hdl.handle.net/21.15107/rcub_cherry_752 .

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