Repeated examination of the aerial parts of Hypericum Perfomtum yielded a new degradation product of hyperforin (1) namely deoxyfurohyperforin A (2), together with the previously identified furohyperforin (3), furoadhyperforin (4), furohyperforin A (5a and 5b), pyrano[7,28-b]hyperforin (6) and 3-methyl-4,6-di(3-methyl-2-butenyl)-2-(2-methyl-1-oxopropyl)-3-(4-methyl-3-pentenyl)-cyclohexanone (7). The antimicrobial activity of the compounds 3, 5a and 5b, 6 and 7 was tested against Staphylococcus aureus, Candida albicans, Bacillus subtilis and Escherichia coli. (C) 2003 Elsevier Science B.V. All rights reserved.
Keywords:
Hypericum perforatum / deoxyfurohyperforin A / antimicrobial activity
TY - JOUR
AU - Vajs, Vlatka
AU - Vugdelija, S
AU - Trifunović, Snežana S.
AU - Karadžić, Ivanka M.
AU - Juranic, N
AU - Macura, S
AU - Milosavljevic, Slobodan
PY - 2003
UR - https://cer.ihtm.bg.ac.rs/handle/123456789/4156
AB - Repeated examination of the aerial parts of Hypericum Perfomtum yielded a new degradation product of hyperforin (1) namely deoxyfurohyperforin A (2), together with the previously identified furohyperforin (3), furoadhyperforin (4), furohyperforin A (5a and 5b), pyrano[7,28-b]hyperforin (6) and 3-methyl-4,6-di(3-methyl-2-butenyl)-2-(2-methyl-1-oxopropyl)-3-(4-methyl-3-pentenyl)-cyclohexanone (7). The antimicrobial activity of the compounds 3, 5a and 5b, 6 and 7 was tested against Staphylococcus aureus, Candida albicans, Bacillus subtilis and Escherichia coli. (C) 2003 Elsevier Science B.V. All rights reserved.
PB - Elsevier
T2 - Fitoterapia
T1 - Further degradation product of hyperforin from Hypericum perforatum (St. John's Wort)
VL - 74
IS - 5
SP - 439
EP - 444
DO - 10.1016/S0367-326X(03)00114-X
ER -
@article{
author = "Vajs, Vlatka and Vugdelija, S and Trifunović, Snežana S. and Karadžić, Ivanka M. and Juranic, N and Macura, S and Milosavljevic, Slobodan",
year = "2003",
abstract = "Repeated examination of the aerial parts of Hypericum Perfomtum yielded a new degradation product of hyperforin (1) namely deoxyfurohyperforin A (2), together with the previously identified furohyperforin (3), furoadhyperforin (4), furohyperforin A (5a and 5b), pyrano[7,28-b]hyperforin (6) and 3-methyl-4,6-di(3-methyl-2-butenyl)-2-(2-methyl-1-oxopropyl)-3-(4-methyl-3-pentenyl)-cyclohexanone (7). The antimicrobial activity of the compounds 3, 5a and 5b, 6 and 7 was tested against Staphylococcus aureus, Candida albicans, Bacillus subtilis and Escherichia coli. (C) 2003 Elsevier Science B.V. All rights reserved.",
publisher = "Elsevier",
journal = "Fitoterapia",
title = "Further degradation product of hyperforin from Hypericum perforatum (St. John's Wort)",
volume = "74",
number = "5",
pages = "439-444",
doi = "10.1016/S0367-326X(03)00114-X"
}
Vajs, V., Vugdelija, S., Trifunović, S. S., Karadžić, I. M., Juranic, N., Macura, S.,& Milosavljevic, S.. (2003). Further degradation product of hyperforin from Hypericum perforatum (St. John's Wort). in Fitoterapia
Elsevier., 74(5), 439-444.
https://doi.org/10.1016/S0367-326X(03)00114-X
Vajs V, Vugdelija S, Trifunović SS, Karadžić IM, Juranic N, Macura S, Milosavljevic S. Further degradation product of hyperforin from Hypericum perforatum (St. John's Wort). in Fitoterapia. 2003;74(5):439-444.
doi:10.1016/S0367-326X(03)00114-X .
Vajs, Vlatka, Vugdelija, S, Trifunović, Snežana S., Karadžić, Ivanka M., Juranic, N, Macura, S, Milosavljevic, Slobodan, "Further degradation product of hyperforin from Hypericum perforatum (St. John's Wort)" in Fitoterapia, 74, no. 5 (2003):439-444,
https://doi.org/10.1016/S0367-326X(03)00114-X . .
