As shown by quantitative 1H NMR measurements, a lipophilic extract of the aerial parts of Hypericum atomarium ssp. degenii contained a high percentage (3.1% per weight of dried plant material) of a prenylated phloroglucinol (1). Compound 1, named hyperatomarin, occurring in two tautomeric forms (1a ⇆ 1b), was isolated by bioactivity-guided preparative TLC and was identified on the basis of spectral data interpretation. This isolated phloroglucinol exhibited activity against Gram-positive (Staphyloccocus aureus and Microccocus luteus) and Gram-positive spore-forming bacteria (Bacillus subtilis and B. IP 5832).
TY - JOUR
AU - Savikin-Fodulovic, K
AU - Aljančić, Ivana
AU - Vajs, Vlatka
AU - Menkonic, N
AU - Macura, S
AU - Gojgić-Cvijović, Gordana
AU - Milosavljević, Slobodan
PY - 2003
UR - https://cer.ihtm.bg.ac.rs/handle/123456789/4155
AB - As shown by quantitative 1H NMR measurements, a lipophilic extract of the aerial parts of Hypericum atomarium ssp. degenii contained a high percentage (3.1% per weight of dried plant material) of a prenylated phloroglucinol (1). Compound 1, named hyperatomarin, occurring in two tautomeric forms (1a ⇆ 1b), was isolated by bioactivity-guided preparative TLC and was identified on the basis of spectral data interpretation. This isolated phloroglucinol exhibited activity against Gram-positive (Staphyloccocus aureus and Microccocus luteus) and Gram-positive spore-forming bacteria (Bacillus subtilis and B. IP 5832).
PB - American Chemical Society (ACS)
T2 - Journal of Natural Products
T1 - Hyperatomarin, an antibacterial prenylated phloroglucinol from Hypericum atomarium ssp degenii
VL - 66
IS - 9
SP - 1236
EP - 1238
DO - 10.1021/np030131o
ER -
@article{
author = "Savikin-Fodulovic, K and Aljančić, Ivana and Vajs, Vlatka and Menkonic, N and Macura, S and Gojgić-Cvijović, Gordana and Milosavljević, Slobodan",
year = "2003",
url = "https://cer.ihtm.bg.ac.rs/handle/123456789/4155",
abstract = "As shown by quantitative 1H NMR measurements, a lipophilic extract of the aerial parts of Hypericum atomarium ssp. degenii contained a high percentage (3.1% per weight of dried plant material) of a prenylated phloroglucinol (1). Compound 1, named hyperatomarin, occurring in two tautomeric forms (1a ⇆ 1b), was isolated by bioactivity-guided preparative TLC and was identified on the basis of spectral data interpretation. This isolated phloroglucinol exhibited activity against Gram-positive (Staphyloccocus aureus and Microccocus luteus) and Gram-positive spore-forming bacteria (Bacillus subtilis and B. IP 5832).",
publisher = "American Chemical Society (ACS)",
journal = "Journal of Natural Products",
title = "Hyperatomarin, an antibacterial prenylated phloroglucinol from Hypericum atomarium ssp degenii",
volume = "66",
number = "9",
pages = "1236-1238",
doi = "10.1021/np030131o"
}
Savikin-Fodulovic K, Aljančić I, Vajs V, Menkonic N, Macura S, Gojgić-Cvijović G, Milosavljević S. Hyperatomarin, an antibacterial prenylated phloroglucinol from Hypericum atomarium ssp degenii. Journal of Natural Products. 2003;66(9):1236-1238
Savikin-Fodulovic, K., Aljančić, I., Vajs, V., Menkonic, N., Macura, S., Gojgić-Cvijović, G.,& Milosavljević, S. (2003). Hyperatomarin, an antibacterial prenylated phloroglucinol from Hypericum atomarium ssp degenii.
Journal of Natural ProductsAmerican Chemical Society (ACS)., 66(9), 1236-1238.
https://doi.org/10.1021/np030131o
Savikin-Fodulovic K, Aljančić Ivana, Vajs Vlatka, Menkonic N, Macura S, Gojgić-Cvijović Gordana, Milosavljević Slobodan, "Hyperatomarin, an antibacterial prenylated phloroglucinol from Hypericum atomarium ssp degenii" 66, no. 9 (2003):1236-1238,
https://doi.org/10.1021/np030131o .
