Mixed cobalt(III) complexes with aromatic amino acids and diamine. Part IV. Influence of noncovalent intraand interligand interactions on rotamer population of the S-phenylalaninato and S-tyrosinato side groups in (1,2-diaminoethane)bis(S-aminocarboxylato)cobalt(III) complexes
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Authors
Miodragović, Đenana
Milosavljević, Slobodan

Malinar, Mijat J
Ćelap, Milenko B
Todorović, Nina

Juranić, Nenad
Article (Published version)

Taylor & Francis
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Rotamer population of S -tyrosinato and S -phenylalaninato ligands side groups in diastereomers of (1,2-diaminoethane) bis ( S -aminocarboxylato)cobalt(III) complexes is calculated by vicinal and proton coupling constant analysis. The effect of noncovalent intra- and interligand interactions on the population of rotamers in D 2 O solution is discussed. It has been established that in all the complexes investigated the most abundant is rotamer t , in which aromatic voluminous moiety and carboxylic group are in an anti position. In almost all complexes the lowest content is of rotamer g , in which these two groups are in the nearest position. Relatively high population of rotamer h in complex 5 tyr , in spite of high steric hindrances, is due to intra- and interligand NH interactions.
Keywords:
Cobalt(III) Complex Diastereomers / Conformational Analysis / NMR / Nh…π Interactions / S -phenylalanine / S -tyrosineSource:
Enantiomer, 2002, 7, 6, 375-382Publisher:
- Taylor & Francis
DOI: 10.1080/10242430215714
ISSN: 1024-2430
PubMed: 12643314