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Exposure of Mn and FeSODs, but not Cu/ZnSOD, to NO leads to nitrosonium and nitroxyl ions generation which cause enzyme modification and inactivation: an in vitro study
(Elsevier, 1999)
The effect of NO treatment in vitro on structural and functional alterations of Cu/Zn, Mn, and Fe type of
SODs was studied. Significant difference in response to NO of Cu/ZnSOD compared to the Mn and Fe types was
demonstrated. ...