Synthesis and Antimicrobial Activity of (3-Formyl-4-hydroxybenzyl)triphenylphosphonium Chloride Acylhydrazones
Abstract
In this study, four novel quaternary phosphonium acylhydrazones, derivatives of (3-formyl-4-hydroxybenzyl)triphenylphosphonium chloride, have been synthesized and their structures elucidated from IR and NMR spectra, and elemental analysis. All synthesized compounds have been tested for their antimicrobial activity, and acylhydrazones have demonstrated selective activity against Gram-positive bacteria strains.
Keywords:
delocalized lipophilic cations / hydrazones / antimicrobial activity / triphenylphosphonium ionsSource:
Russian Journal of General Chemistry, 2020, 90, 9, 1716-1720Publisher:
- Springer
Funding / projects:
DOI: 10.1134/S1070363220090194
ISSN: 1070-3632; 1608-3350
WoS: 000576839200019
Scopus: 2-s2.0-85092293555
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Institution/Community
IHTMTY - JOUR AU - Milenković, Milica R. AU - Živković-Radovanović, Vukosava AU - Anđelković, Ljubica PY - 2020 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/3710 AB - In this study, four novel quaternary phosphonium acylhydrazones, derivatives of (3-formyl-4-hydroxybenzyl)triphenylphosphonium chloride, have been synthesized and their structures elucidated from IR and NMR spectra, and elemental analysis. All synthesized compounds have been tested for their antimicrobial activity, and acylhydrazones have demonstrated selective activity against Gram-positive bacteria strains. PB - Springer T2 - Russian Journal of General Chemistry T1 - Synthesis and Antimicrobial Activity of (3-Formyl-4-hydroxybenzyl)triphenylphosphonium Chloride Acylhydrazones VL - 90 IS - 9 SP - 1716 EP - 1720 DO - 10.1134/S1070363220090194 ER -
@article{ author = "Milenković, Milica R. and Živković-Radovanović, Vukosava and Anđelković, Ljubica", year = "2020", abstract = "In this study, four novel quaternary phosphonium acylhydrazones, derivatives of (3-formyl-4-hydroxybenzyl)triphenylphosphonium chloride, have been synthesized and their structures elucidated from IR and NMR spectra, and elemental analysis. All synthesized compounds have been tested for their antimicrobial activity, and acylhydrazones have demonstrated selective activity against Gram-positive bacteria strains.", publisher = "Springer", journal = "Russian Journal of General Chemistry", title = "Synthesis and Antimicrobial Activity of (3-Formyl-4-hydroxybenzyl)triphenylphosphonium Chloride Acylhydrazones", volume = "90", number = "9", pages = "1716-1720", doi = "10.1134/S1070363220090194" }
Milenković, M. R., Živković-Radovanović, V.,& Anđelković, L.. (2020). Synthesis and Antimicrobial Activity of (3-Formyl-4-hydroxybenzyl)triphenylphosphonium Chloride Acylhydrazones. in Russian Journal of General Chemistry Springer., 90(9), 1716-1720. https://doi.org/10.1134/S1070363220090194
Milenković MR, Živković-Radovanović V, Anđelković L. Synthesis and Antimicrobial Activity of (3-Formyl-4-hydroxybenzyl)triphenylphosphonium Chloride Acylhydrazones. in Russian Journal of General Chemistry. 2020;90(9):1716-1720. doi:10.1134/S1070363220090194 .
Milenković, Milica R., Živković-Radovanović, Vukosava, Anđelković, Ljubica, "Synthesis and Antimicrobial Activity of (3-Formyl-4-hydroxybenzyl)triphenylphosphonium Chloride Acylhydrazones" in Russian Journal of General Chemistry, 90, no. 9 (2020):1716-1720, https://doi.org/10.1134/S1070363220090194 . .