dc.creator | Ognjanović, Miloš | |
dc.creator | Stanković, Vesna | |
dc.creator | Knežević, Sara | |
dc.creator | Antić, Bratislav | |
dc.creator | Vranješ-Đurić, Sanja | |
dc.creator | Stanković, Dalibor | |
dc.date.accessioned | 2020-07-17T08:37:09Z | |
dc.date.available | 2020-07-17T08:37:09Z | |
dc.date.issued | 2020 | |
dc.identifier.issn | 0026-265X | |
dc.identifier.uri | https://cer.ihtm.bg.ac.rs/handle/123456789/3594 | |
dc.description.abstract | Herein, we proposed a novel approach and state-of-the-art technology for the improvement of the materials and
enzyme immobilization at the electrode surface and construction of impedimetric glucose biosensor. We silanized
titanium dioxide nanoparticles using (3-aminopropyl)triethoxysilane (APTES), for the preparation of crosslinked
material nanoparticles, with carboxylic graphene. The silanization of titanium dioxide nanoparticles and
an increase in electron shuttle was proven feasible when this composite was able to achieve about 30% higher
current than non-silanized material. The proposed approach was used for the modification of the printed threeelectrode
system and the development of the impedimetric glucose biosensor. The material morphology and
electrochemical characteristics were confirmed by spectroscopic and electrochemical methods. The present
combination effectively modified the electrode surface and serve as a promising basis for the construction of
Point-of-Care devices. Developed biosensor possesses wide operating linear range toward glucose detection from
50 μmol to 1000 μmol, with the limit of detection of 24 μmol. Finally, negligible interference effect and application
in the real sample indicate that the proposed mechanism can be successfully applied to the assessment
of glucose level in only one drop of real sample. | en |
dc.language.iso | en | sr |
dc.publisher | Elsevier | sr |
dc.relation | EUREKA project E! 13303 MED-BIO-TEST | sr |
dc.rights | restrictedAccess | sr |
dc.source | Microchemical Journal | sr |
dc.subject | Titanium dioxide | sr |
dc.subject | Carboxylic graphene | sr |
dc.subject | APTES | sr |
dc.subject | Cross-linking | sr |
dc.subject | Impedimetric biosensor | sr |
dc.title | TiO2/APTES cross-linked to carboxylic graphene based impedimetric glucose biosensor | sr |
dc.type | article | sr |
dc.rights.license | ARR | sr |
dcterms.abstract | Огњановић, Милош; Aнтић, Братислав; Станковић, Весна; Врањеш-Ђурић, Сања; Кнежевић, Сара; Станковић, Далибор; | |
dc.rights.holder | Elsevier | sr |
dc.citation.volume | 158 | |
dc.citation.spage | 105150 | |
dc.citation.rank | M21~ | |
dc.identifier.doi | 10.1016/j.microc.2020.105150 | |
dc.identifier.scopus | 2-s2.0-85086377141 | |
dc.identifier.wos | 000573647400007 | |
dc.type.version | publishedVersion | sr |