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dc.creatorOgnjanović, Miloš
dc.creatorStanković, Vesna
dc.creatorKnežević, Sara
dc.creatorAntić, Bratislav
dc.creatorVranješ-Đurić, Sanja
dc.creatorStanković, Dalibor
dc.date.accessioned2020-07-17T08:37:09Z
dc.date.available2020-07-17T08:37:09Z
dc.date.issued2020
dc.identifier.issn0026-265X
dc.identifier.urihttp://cer.ihtm.bg.ac.rs/handle/123456789/3594
dc.description.abstractHerein, we proposed a novel approach and state-of-the-art technology for the improvement of the materials and enzyme immobilization at the electrode surface and construction of impedimetric glucose biosensor. We silanized titanium dioxide nanoparticles using (3-aminopropyl)triethoxysilane (APTES), for the preparation of crosslinked material nanoparticles, with carboxylic graphene. The silanization of titanium dioxide nanoparticles and an increase in electron shuttle was proven feasible when this composite was able to achieve about 30% higher current than non-silanized material. The proposed approach was used for the modification of the printed threeelectrode system and the development of the impedimetric glucose biosensor. The material morphology and electrochemical characteristics were confirmed by spectroscopic and electrochemical methods. The present combination effectively modified the electrode surface and serve as a promising basis for the construction of Point-of-Care devices. Developed biosensor possesses wide operating linear range toward glucose detection from 50 μmol to 1000 μmol, with the limit of detection of 24 μmol. Finally, negligible interference effect and application in the real sample indicate that the proposed mechanism can be successfully applied to the assessment of glucose level in only one drop of real sample.en
dc.language.isoensr
dc.publisherElseviersr
dc.relationEUREKA project E! 13303 MED-BIO-TESTsr
dc.rightsrestrictedAccesssr
dc.sourceMicrochemical Journalsr
dc.subjectTitanium dioxidesr
dc.subjectCarboxylic graphenesr
dc.subjectAPTESsr
dc.subjectCross-linkingsr
dc.subjectImpedimetric biosensorsr
dc.titleTiO2/APTES cross-linked to carboxylic graphene based impedimetric glucose biosensorsr
dc.typearticlesr
dc.rights.licenseARRsr
dcterms.abstractОгњановић, Милош; Aнтић, Братислав; Станковић, Весна; Врањеш-Ђурић, Сања; Кнежевић, Сара; Станковић, Далибор;
dc.rights.holderElseviersr
dc.citation.volume158
dc.citation.spage105150
dc.citation.rankM21~
dc.identifier.doi10.1016/j.microc.2020.105150
dc.identifier.scopus2-s2.0-8508637714
dc.identifier.wos000573647400007
dc.type.versionpublishedVersionsr


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