Show simple item record

dc.creatorVujić, Bojan
dc.creatorVidaković, Vera
dc.creatorJadranin, Milka
dc.creatorNovaković, Irena
dc.creatorTrifunović, Snežana
dc.creatorTešević, Vele
dc.creatorMandić, Boris
dc.date.accessioned2020-06-26T10:11:49Z
dc.date.available2020-06-26T10:11:49Z
dc.date.issued2020
dc.identifier.issn2223-7747
dc.identifier.urihttp://cherry.chem.bg.ac.rs/handle/123456789/3962
dc.identifier.urihttp://ibiss-r.rcub.bg.ac.rs/handle/123456789/3620
dc.identifier.urihttp://cer.ihtm.bg.ac.rs/handle/123456789/3581
dc.description.abstractHelichrysum plicatum DC. is widely used in folk medicine in treating a variety of health disorders. The aim of this study was to examine the influence of different extraction solvents on the chemical composition, antioxidant potential, and antimicrobial activities of H. plicatum. Aerial parts were separately extracted with ethanol, dichloromethane, and sunflower oil. The oil extract (OE) was re-extracted with acetonitrile. A total of 142 compounds were tentatively identified in ethanolic (EE), dichloromethane (DCME), and acetonitrile (ACNE) extracts using HPLC-DAD/ESI-ToF-MS. The dominant compound class in all extracts were α-pyrones, alongside flavonoids in EE, terpenoids in DCME and ACNE, and phloroglucinols in DCME. The antioxidant potential of the extracts was assessed by the 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) assay. EE and DCME possessed the most potent radical scavenging capacity. Antimicrobial activity was investigated on eight bacterial, two yeast, and one fungal species. All extracts exhibited high antifungal and notable antibacterial activities compared to control substances, with DCME being the most potent. DCME exhibited stronger antimicrobial activity against P. aeruginosa than the standard chloramphenicol.sr
dc.language.isoensr
dc.publisherMDPIsr
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172053/RS//sr
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173011/RS//sr
dc.rightsopenAccesssr
dc.sourcePlantssr
dc.subjectAntimicrobial activitysr
dc.subjectAntioxidant potentialsr
dc.subjectHelichrysum plicatumsr
dc.subjectLiquid chromatography-mass spectrometry (LC-MS)sr
dc.subjectPhenolssr
dc.subjectSolvent polaritysr
dc.titleComposition, Antioxidant Potential, and Antimicrobial Activity of Helichrysum plicatum DC. Various Extractssr
dc.typearticlesr
dc.rights.licenseBYsr
dcterms.abstractЈадранин, Милка; Новаковић, Ирена; Трифуновић, Снежана; Тешевић, Веле; Мандић, Борис; Вујић, Бојан; Видаковић, Вера;
dc.citation.volume9
dc.citation.issue3
dc.citation.spage337
dc.citation.rankM21~
dc.identifier.doi10.3390/plants9030337
dc.identifier.fulltexthttp://cer.ihtm.bg.ac.rs/bitstream/id/16629/Composition_Antioxidant_Potential_pub_2020.pdf
dc.identifier.scopus2-s2.0-85082197649
dc.identifier.wos000525315000029
dc.type.versionpublishedVersionsr


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record