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dc.creatorDrakulić, Branko
dc.creatorJuranić, Ivan
dc.creatorErić, Slavica
dc.creatorZloh, Mire
dc.date.accessioned2020-05-04T07:26:10Z
dc.date.available2020-05-04T07:26:10Z
dc.date.issued2008
dc.identifier.issn0378-5173
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/1029
dc.identifier.urihttp://cer.ihtm.bg.ac.rs/handle/123456789/3512
dc.description.abstractThe use of chemical penetration enhancers (CPE) is growing due to their ability to improve drug delivery through the skin. A possible mechanism of penetration enhancement could involve the complex formation between drug and components in the pharmaceutical formulation, thus altering the physicochemical properties of the active substance. Here, modelling studies indicate that hydrocarbon and oxygen-containing terpenes (penetration enhancers) could form complexes with drugs. Satisfactory correlations have been obtained between the predicted molecular properties of enhancers and their enhancement effects. Crown Copyrighten
dc.publisherElsevier Science BV, Amsterdam
dc.relationinfo:eu-repo/grantAgreement/MESTD/MPN2006-2010/142010/RS//
dc.rightsrestrictedAccess
dc.sourceInternational Journal of Pharmaceutics
dc.subjectConformational searchen
dc.subjectSmall molecule-small moleculeen
dc.subjectinteractionsen
dc.subjectTransdermal deliveryen
dc.subjectPenetration enhancersen
dc.titleRole of complexes formation between drugs and penetration enhancers in transdermal deliveryen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractЈуранић, Иван; Дракулић, Бранко; Злох, Мире; Ерић, Славица;
dc.citation.volume363
dc.citation.issue1-2
dc.citation.spage40
dc.citation.epage49
dc.citation.other363(1-2): 40-49
dc.citation.rankM22
dc.identifier.pmid18675333
dc.identifier.doi10.1016/j.ijpharm.2008.06.032
dc.identifier.rcubconv_2087
dc.identifier.scopus2-s2.0-51749091289
dc.identifier.wos000260478700003
dc.type.versionpublishedVersion


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