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dc.creatorHusinec, Suren
dc.creatorSavić, Vladimir
dc.creatorSimić, Milena R.
dc.creatorTešević, Vele
dc.creatorVidović, Dragoslav
dc.date.accessioned2020-05-01T07:32:07Z
dc.date.available2020-05-01T07:32:07Z
dc.date.issued2011
dc.identifier.issn0040-4039
dc.identifier.urihttp://cherry.chem.bg.ac.rs/handle/123456789/1342
dc.identifier.urihttps://cer.ihtm.bg.ac.rs/handle/123456789/3505
dc.identifier.urihttp://farfar.pharmacy.bg.ac.rs/handle/123456789/1567
dc.description.abstractAnnulation processes of isoquinoline and p-carboline compounds have been investigated leading to synthetic routes for the preparation of 8-oxoprotoberberine derivatives. The key steps combined a diene formation/Diels-Alder cycloaddition reaction to afford the targeted polycyclic skeletons. Further oxidative transformations of the cycloadducts produced the 8-oxoprotoberberine type products. The alkaloids of this class are important natural products with a wide range of biological activity and the synthethic methodology described in this paper could prove to be useful for the preparation of the D-ring functionalised derivatives.en
dc.publisherOxford : Pergamon-Elsevier Science Ltd
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172009/RS//
dc.relationNTU (SPMS)
dc.relationNTU (CBC)
dc.rightsrestrictedAccess
dc.sourceTetrahedron Letters
dc.subjectIsoquinolineen
dc.subjectAnnulationsen
dc.subject8-Oxoprotoberberine skeletonsen
dc.subjectSynthesisen
dc.titleAnnulations of isoquinoline and beta-carboline ring systems: synthesis of 8-oxoprotoberberine derivativesen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractХусинец, Сурен; Савић, Владимир; Видовић, Драгослав; Тешевић, Веле; Симић, Милена Р.;
dc.citation.volume52
dc.citation.issue21
dc.citation.spage2733
dc.citation.epage2736
dc.citation.other52(21): 2733-2736
dc.citation.rankM22
dc.identifier.doi10.1016/j.tetlet.2011.03.085
dc.identifier.rcubKon_2180
dc.identifier.scopus2-s2.0-79955483488
dc.identifier.wos000290602100030
dc.type.versionpublishedVersionen


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