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Annulations of isoquinoline and beta-carboline ring systems: synthesis of 8-oxoprotoberberine derivatives
dc.creator | Husinec, Suren | |
dc.creator | Savić, Vladimir | |
dc.creator | Simić, Milena R. | |
dc.creator | Tešević, Vele | |
dc.creator | Vidović, Dragoslav | |
dc.date.accessioned | 2020-05-01T07:32:07Z | |
dc.date.available | 2020-05-01T07:32:07Z | |
dc.date.issued | 2011 | |
dc.identifier.issn | 0040-4039 | |
dc.identifier.uri | http://cherry.chem.bg.ac.rs/handle/123456789/1342 | |
dc.identifier.uri | https://cer.ihtm.bg.ac.rs/handle/123456789/3505 | |
dc.identifier.uri | http://farfar.pharmacy.bg.ac.rs/handle/123456789/1567 | |
dc.description.abstract | Annulation processes of isoquinoline and p-carboline compounds have been investigated leading to synthetic routes for the preparation of 8-oxoprotoberberine derivatives. The key steps combined a diene formation/Diels-Alder cycloaddition reaction to afford the targeted polycyclic skeletons. Further oxidative transformations of the cycloadducts produced the 8-oxoprotoberberine type products. The alkaloids of this class are important natural products with a wide range of biological activity and the synthethic methodology described in this paper could prove to be useful for the preparation of the D-ring functionalised derivatives. | en |
dc.publisher | Oxford : Pergamon-Elsevier Science Ltd | |
dc.relation | info:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172009/RS// | |
dc.relation | NTU (SPMS) | |
dc.relation | NTU (CBC) | |
dc.rights | restrictedAccess | |
dc.source | Tetrahedron Letters | |
dc.subject | Isoquinoline | en |
dc.subject | Annulations | en |
dc.subject | 8-Oxoprotoberberine skeletons | en |
dc.subject | Synthesis | en |
dc.title | Annulations of isoquinoline and beta-carboline ring systems: synthesis of 8-oxoprotoberberine derivatives | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Хусинец, Сурен; Савић, Владимир; Видовић, Драгослав; Тешевић, Веле; Симић, Милена Р.; | |
dc.citation.volume | 52 | |
dc.citation.issue | 21 | |
dc.citation.spage | 2733 | |
dc.citation.epage | 2736 | |
dc.citation.other | 52(21): 2733-2736 | |
dc.citation.rank | M22 | |
dc.identifier.doi | 10.1016/j.tetlet.2011.03.085 | |
dc.identifier.scopus | 2-s2.0-79955483488 | |
dc.identifier.wos | 000290602100030 | |
dc.type.version | publishedVersion | en |