The synthesis of some unsaturated 4-substituted-g-lactones

Abstract

The synthesis of conjugated and nonconjugated unsaturated 4-substituted lactones of type 1 and 2 are described. The type 1 lactone was prepared by a two step procedure employing Bredereck s reagent. The type 2 lactone was synthesised by combining the Claisen-Ireland rearrangement and selenolactonisation.

Razvijeni su relativno jednostavni sintetski putevi za dobijanje konjugovanih i nekonjugovanih d-laktona koji imaju strukture tipa 1 i 2. Lakton tipa 1 je sintetisan uvodjenjem egzociklične dvostruke veze uz korišćenje Bredereck-ovog reagensa, dok je lakton tipa 2 dobijen primenom Claisen-Ireland-ovog premeštanja i selenolaktonizacije.