Microbiological transformation of a synthetic benzofurane type lactone

Abstract

The aim of this work was the investigation of the biotransformation ability of a synthetic benzofurane type g-lactone. This workwas basedon the microbiological reactions of Aspergillus niger, Saccharomyces cerevisiae, Bacillus mycoides, Agrobacterium tumefa- ciens,Pseudomonas glicinea and Pseudomonas fluorescens to obtain newactive derivatives. Four biotransformation products were determined. The lactone was used for two purposes, as an additive for the nutrient substrate and as a source of organic carbon.

Cilj ovog rada je ispitivanje mogućnosti biotransformacije benzofuranskog derivata, sa a-metilen-g-butirolaktonskom strukturnom jedinicom, sa različitim sojevima mikroorganizama: Aspergillus niger, Saccharomyces cerrevisiae, Bacillus mycoides, Agrobacterium tumefaciens, Pseudomonas glicinea i Pseudomonas fluorescens u cilju dobivanja novih jedinjenja sa specifičnijom antimikrobnom aktivnošću. Takodje izolovani i identifikovani proizvodi su ukazali i potvrdili osnovne biodegradacione puteve ispitivanog laktona.