Microbiological transformation of a synthetic benzofurane type lactone
Mikrobiološka transformacija sintetičkog laktona benzofuranskog tipa
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The aim of this work was the investigation of the biotransformation ability of a
synthetic benzofurane type g-lactone. This workwas basedon the microbiological reactions
of Aspergillus niger, Saccharomyces cerevisiae, Bacillus mycoides, Agrobacterium tumefa-
ciens,Pseudomonas glicinea and Pseudomonas fluorescens to obtain newactive derivatives.
Four biotransformation products were determined. The lactone was used for two purposes,
as an additive for the nutrient substrate and as a source of organic carbon.
Cilj ovog rada je ispitivanje mogućnosti biotransformacije benzofuranskog
derivata, sa a-metilen-g-butirolaktonskom strukturnom jedinicom, sa različitim sojevima
mikroorganizama: Aspergillus niger, Saccharomyces cerrevisiae, Bacillus mycoides, Agrobacterium
tumefaciens, Pseudomonas glicinea i Pseudomonas fluorescens u cilju dobivanja novih
jedinjenja sa specifičnijom antimikrobnom aktivnošću. Takodje izolovani i identifikovani
proizvodi su ukazali i potvrdili osnovne biodegradacione puteve ispitivanog laktona.
Keywords:
synthesis / g-lactone / biotransformation / d-lactoneSource:
Journal of the Serbian Chemical Society, 2000, 65, 2, 103-111Publisher:
- Belgrade : Serbian Chemical Society
DOI: 10.2298/JSC0002103S
ISSN: 0352-5139; 1820-7421