In this study, three tetracyclic triterpenes: (3S,24S)-tirucall-7-ene-3,24,25-triol (1), (3S,24R)-tirucall-7-ene-3,24,25-triol (2) and inoterpene C (3), were isolated from the milkweed Euphorbia nicaeensis All. using dry-column flash silica gel chromatography and semipreparative normal-phase HPLC. Their structures were determined on the basis of 1D and 2D NMR spectra and literature review. Although these three compounds have previously been isolated from other plant species, this is the first time that they have been isolated from E. nicaeensis.
U ovom radu, tri tetraciklična triterpena: (3S,24S)-tirukal-7-en-3,24,25-triol (1), (3S,24R)-tirukal-7-en-3,24,25-triol (2) i inoterpen C (3) su izolovana iz mlečike Euphorbia nicaeensis All. koristeći brzu hromatografiju na suvom stubu silika gela i semipreparativnu normalno-faznu HPLC. Strukture su određene na osnovu 1D i 2D NMR spektara i poređenjem sa literaturom. Iako su ova tri jedinjenja ranije izolovana iz drugih biljnih vrsta, ovo je prvi put da su izolovana iz E. nicaeensis.
TY - JOUR
AU - Krstić, Gordana
AU - Novaković, Miroslav
AU - Jadranin, Milka
AU - Tešević, Vele
PY - 2019
UR - http://cer.ihtm.bg.ac.rs/handle/123456789/3471
AB - In this study, three tetracyclic triterpenes: (3S,24S)-tirucall-7-ene-3,24,25-triol (1), (3S,24R)-tirucall-7-ene-3,24,25-triol (2) and inoterpene C (3), were isolated from the milkweed Euphorbia nicaeensis All. using dry-column flash silica gel chromatography and semipreparative normal-phase HPLC. Their structures were determined on the basis of 1D and 2D NMR spectra and literature review. Although these three compounds have previously been isolated from other plant species, this is the first time that they have been isolated from E. nicaeensis.
AB - U ovom radu, tri tetraciklična triterpena: (3S,24S)-tirukal-7-en-3,24,25-triol (1), (3S,24R)-tirukal-7-en-3,24,25-triol (2) i inoterpen C (3) su izolovana iz mlečike Euphorbia nicaeensis All. koristeći brzu hromatografiju na suvom stubu silika gela i semipreparativnu normalno-faznu HPLC. Strukture su određene na osnovu 1D i 2D NMR spektara i poređenjem sa literaturom. Iako su ova tri jedinjenja ranije izolovana iz drugih biljnih vrsta, ovo je prvi put da su izolovana iz E. nicaeensis.
PB - Leskovac: University of Niš - Faculty of Technology, Leskovac
T2 - Advanced Technologies
T1 - Tetracyclic triterpenoids from Euphorbia nicaeensis All
T1 - Tetraciklični triterpenoidi iz vrste Euphorbia nicaeensis All
VL - 8
IS - 2
SP - 37
EP - 45
DO - 10.5937/savteh1902037K
ER -
@article{
author = "Krstić, Gordana and Novaković, Miroslav and Jadranin, Milka and Tešević, Vele",
year = "2019",
url = "http://cer.ihtm.bg.ac.rs/handle/123456789/3471",
abstract = "In this study, three tetracyclic triterpenes: (3S,24S)-tirucall-7-ene-3,24,25-triol (1), (3S,24R)-tirucall-7-ene-3,24,25-triol (2) and inoterpene C (3), were isolated from the milkweed Euphorbia nicaeensis All. using dry-column flash silica gel chromatography and semipreparative normal-phase HPLC. Their structures were determined on the basis of 1D and 2D NMR spectra and literature review. Although these three compounds have previously been isolated from other plant species, this is the first time that they have been isolated from E. nicaeensis., U ovom radu, tri tetraciklična triterpena: (3S,24S)-tirukal-7-en-3,24,25-triol (1), (3S,24R)-tirukal-7-en-3,24,25-triol (2) i inoterpen C (3) su izolovana iz mlečike Euphorbia nicaeensis All. koristeći brzu hromatografiju na suvom stubu silika gela i semipreparativnu normalno-faznu HPLC. Strukture su određene na osnovu 1D i 2D NMR spektara i poređenjem sa literaturom. Iako su ova tri jedinjenja ranije izolovana iz drugih biljnih vrsta, ovo je prvi put da su izolovana iz E. nicaeensis.",
publisher = "Leskovac: University of Niš - Faculty of Technology, Leskovac",
journal = "Advanced Technologies",
title = "Tetracyclic triterpenoids from Euphorbia nicaeensis All, Tetraciklični triterpenoidi iz vrste Euphorbia nicaeensis All",
volume = "8",
number = "2",
pages = "37-45",
doi = "10.5937/savteh1902037K"
}
Krstić, G., Novaković, M., Jadranin, M.,& Tešević, V. (2019). Tetraciklični triterpenoidi iz vrste Euphorbia nicaeensis All.
Advanced Technologies
Leskovac: University of Niš - Faculty of Technology, Leskovac., 8(2), 37-45.
https://doi.org/10.5937/savteh1902037K
Krstić G, Novaković M, Jadranin M, Tešević V. Tetraciklični triterpenoidi iz vrste Euphorbia nicaeensis All. Advanced Technologies. 2019;8(2):37-45
Krstić Gordana, Novaković Miroslav, Jadranin Milka, Tešević Vele, "Tetraciklični triterpenoidi iz vrste Euphorbia nicaeensis All" Advanced Technologies, 8, no. 2 (2019):37-45,
https://doi.org/10.5937/savteh1902037K .
