Human serum albumin binding of certain antimalarials
Authors
Marković, OliveraCvijetić, Ilija
Zlatović, Mario
Opsenica, Igor
Terzić-Jovanović, Nataša
Šolaja, Bogdan
Verbić, Tatjana
Conference object (Published version)
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Show full item recordAbstract
Tested compounds, previously synthesized, are derivatives of chloroquine, drug commonly used in the treatment and prevention of malaria. Interaction between tested compounds and Human serum albumin (HSA) has been studied by fluorescence spectroscopy in phosphate buffered saline (1× PBS, pH 7.4) . Molecular docking studies were used to determine HSA–compound binding mode.
Keywords:
Human serum albumin / fluorescence spectroscopy / docking / binding modeSource:
4th World Conference on Physico-Chemical Methods in Drug Discovery and Development Red Island, Croatia, September 21-24, 2015 - Book of Abstracts, 2015, 67-67Publisher:
- International Association of Physical Chemists
Funding / projects:
- The synthesis of aminoquinoline-based antimalarials and botulinum neurotoxin A inhibitors (RS-172008)
- Reinforcement of the Faculty of Chemistry, University of Belgrade, towards becoming a Center of Excellence in the region of WB for Molecular Biotechnology and Food research (EU-256716)
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IHTMTY - CONF AU - Marković, Olivera AU - Cvijetić, Ilija AU - Zlatović, Mario AU - Opsenica, Igor AU - Terzić-Jovanović, Nataša AU - Šolaja, Bogdan AU - Verbić, Tatjana PY - 2015 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/3401 AB - Tested compounds, previously synthesized, are derivatives of chloroquine, drug commonly used in the treatment and prevention of malaria. Interaction between tested compounds and Human serum albumin (HSA) has been studied by fluorescence spectroscopy in phosphate buffered saline (1× PBS, pH 7.4) . Molecular docking studies were used to determine HSA–compound binding mode. PB - International Association of Physical Chemists C3 - 4th World Conference on Physico-Chemical Methods in Drug Discovery and Development Red Island, Croatia, September 21-24, 2015 - Book of Abstracts T1 - Human serum albumin binding of certain antimalarials SP - 67 EP - 67 UR - https://hdl.handle.net/21.15107/rcub_cer_3401 ER -
@conference{ author = "Marković, Olivera and Cvijetić, Ilija and Zlatović, Mario and Opsenica, Igor and Terzić-Jovanović, Nataša and Šolaja, Bogdan and Verbić, Tatjana", year = "2015", abstract = "Tested compounds, previously synthesized, are derivatives of chloroquine, drug commonly used in the treatment and prevention of malaria. Interaction between tested compounds and Human serum albumin (HSA) has been studied by fluorescence spectroscopy in phosphate buffered saline (1× PBS, pH 7.4) . Molecular docking studies were used to determine HSA–compound binding mode.", publisher = "International Association of Physical Chemists", journal = "4th World Conference on Physico-Chemical Methods in Drug Discovery and Development Red Island, Croatia, September 21-24, 2015 - Book of Abstracts", title = "Human serum albumin binding of certain antimalarials", pages = "67-67", url = "https://hdl.handle.net/21.15107/rcub_cer_3401" }
Marković, O., Cvijetić, I., Zlatović, M., Opsenica, I., Terzić-Jovanović, N., Šolaja, B.,& Verbić, T.. (2015). Human serum albumin binding of certain antimalarials. in 4th World Conference on Physico-Chemical Methods in Drug Discovery and Development Red Island, Croatia, September 21-24, 2015 - Book of Abstracts International Association of Physical Chemists., 67-67. https://hdl.handle.net/21.15107/rcub_cer_3401
Marković O, Cvijetić I, Zlatović M, Opsenica I, Terzić-Jovanović N, Šolaja B, Verbić T. Human serum albumin binding of certain antimalarials. in 4th World Conference on Physico-Chemical Methods in Drug Discovery and Development Red Island, Croatia, September 21-24, 2015 - Book of Abstracts. 2015;:67-67. https://hdl.handle.net/21.15107/rcub_cer_3401 .
Marković, Olivera, Cvijetić, Ilija, Zlatović, Mario, Opsenica, Igor, Terzić-Jovanović, Nataša, Šolaja, Bogdan, Verbić, Tatjana, "Human serum albumin binding of certain antimalarials" in 4th World Conference on Physico-Chemical Methods in Drug Discovery and Development Red Island, Croatia, September 21-24, 2015 - Book of Abstracts (2015):67-67, https://hdl.handle.net/21.15107/rcub_cer_3401 .