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Antibakterijski efekti novih endodontskih materijala na bazi kalcijum silikata

dc.creatorTrišić, Dijana
dc.creatorĆetenović, Bojana
dc.creatorZdravković, Nemanja
dc.creatorMarković, Tatjana
dc.creatorDojčinović, Biljana
dc.creatorJokanović, Vukoman
dc.creatorMarković, Dejan
dc.date.accessioned2019-12-14T23:00:00Z
dc.date.available2019-12-14T23:00:00Z
dc.date.issued2019
dc.identifier.issn0042-8450
dc.identifier.issn2406-0720
dc.identifier.urihttps://cer.ihtm.bg.ac.rs/handle/123456789/3231
dc.description.abstractBackground/Aim. The main task of endodontic treatment is to eliminate pathologically altered tissue, to disinfect root canal space and to obtain its three-dimensional hermetic obturation. The main purpose of this study was to evaluate antimicrobial activity of new endodontic nano-structured highly active calcium silicates based materials albo-mineral plyoxide carbonate aggregate (ALBO-MPCA) and calcium silicates (CS) in comparison to mineral trioxide aggregate (MTA+) and UltraCal XS (CH). Methods. The antimicrobial activity of materials was tested against Staphylococcus aureus (ATCC 25923) and Enterococcus faecalis (ATCC 14506) strains, and following clinical isolates: Rothia dentocariosa, Enterococcus faecalis, Staphylococcus aureus, Streptococcus anginosus and Streptococcus vestibularis using a double layer agar diffusion test. The pH measurements were performed using the pH meter. Total amount of released ions was determined by inductively coupled plasma optical emission spectrometry (ICP-OES). Results. All tested materials showed the best antibacterial potential after 1 h of incubation. After 3h and 24h of the incubation period, the antibacterial potential of all tested materials were similar. The Agar diffusion test showed that ALBO-MPCA, CS and MTA+ had similar inhibition zones (p > 0.05), except in the activity against Staphylococcus aureus where ALBO-MPCA showed better antimicrobial properties than MTA+ in 3h and 24h of the incubation period (p < 0.05). Following 24h of the incubation, the inhibition zones were the strongest with CH against Staphylococcus aureus (16.67 ± 2.34 mm) followed by ALBO-MPCA (14.67 ± 1.21 mm) and the weakest with CS against Enterococcus faecalis (6.50 ± 1.76 mm). CH showed the highest pH, followed by ALBO-MPCA, CS and MTA+. Conclusion. The expressed antibacterial effects indicate that materials based on nano-structured highly active calcium silicates represent effective therapeutic agents for root canal obturation in one-visit apexification treatment, therefore they are recommend for further examination and clinical trials as they are proposed for MTA substitution.en
dc.publisherMilitary Medical Academy, INIen
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172026/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Technological Development (TD or TR)/31079/RS//
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by-sa/4.0/
dc.sourceVojnosanitetski pregleden
dc.titleAntibacterial effects of new endodontic materials based on calcium silicatesen
dc.titleAntibakterijski efekti novih endodontskih materijala na bazi kalcijum silikatasr
dc.typearticleen
dc.rights.licenseBY-SA
dcterms.abstractМарковић, Татјана; Ћетеновић, Бојана; Тришић, Дијана; Марковић, Дејан; Дојчиновић, Биљана; Здравковић, Немања; Јокановић, Вукоман; Aнтибактеријски ефекти нових ендодонтских материјала на бази калцијум силиката;
dc.rights.holderAuthors
dc.citation.volume76
dc.citation.issue4
dc.citation.spage365
dc.citation.epage372
dc.citation.rankM23~
dc.identifier.doi10.2298/VSP161231130T
dc.identifier.fulltexthttps://cer.ihtm.bg.ac.rs/bitstream/id/15535/1_0042-84501700130T.pdf
dc.identifier.scopus2-s2.0-85069738071
dc.identifier.wos000504432700002
dc.type.versionpublishedVersion


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