Synthesis, characterization and in vitro evaluation of divalent ion release from stable NiFe2O4, ZnFe2O4 and core-shell ZnFe2O4@NiFe2O4 nanoparticles

A simple organic-phase synthesis process was used to produce bare NiFe2O4 and ZnFe2O4 and core-shell ZnFe2O4@NiFe2O4 ferrite nanoparticles. X-ray powder diffractograms for all investigated powders show characteristic peaks of a spinel cubic structure without a secondary phase. Transmission electron microscopy (TEM) indicated the presence of nanoparticles that are smaller than 20 nm. The release of divalent ions (Ni2+ and Zn2+) from synthesized nanoparticles that were dispersed in saline solution, phosphate-buffered saline (PBS) and human serum, as determined by the inductively coupled plasma mass spectrometry (ICP-MS) method, was lower than 2 wt %. These results demonstrate the stability of the investigated nanoparticles in biologically relevant media and exclude the toxicity of Ni2+ and Zn2+ due to metal ion release, thereby opening a broad range of (bio)medical applications.

Ključne reči:

Ferrites / Bimagnetic core-shell nanoparticles / Ni2+ and Zn2+ leakage

Izvor:
Ceramics International, 2020, 46, 3, 3528-3533

Izdavač:

Elsevier

Projekti:

DOI: 10.1016/j.ceramint.2019.10.068

ISSN: 0272-8842

WoS: 000508752000114

Scopus: 2-s2.0-85073150109

[ Google Scholar ]


	5
	3

TY  - JOUR
AU  - Anđelković, Ljubica
AU  - Jeremić, Dejan
AU  - Milenković, Milica R.
AU  - Radosavljević, Jelena
AU  - Vulić, Predrag
AU  - Pavlović, Vladimir B.
AU  - Manojlović, Dragan
AU  - Nikolić, Aleksandar S.
PY  - 2020
UR  - http://cer.ihtm.bg.ac.rs/handle/123456789/3145
AB  - A simple organic-phase synthesis process was used to produce bare NiFe2O4 and ZnFe2O4 and core-shell ZnFe2O4@NiFe2O4 ferrite nanoparticles. X-ray powder diffractograms for all investigated powders show characteristic peaks of a spinel cubic structure without a secondary phase. Transmission electron microscopy (TEM) indicated the presence of nanoparticles that are smaller than 20 nm. The release of divalent ions (Ni2+ and Zn2+) from synthesized nanoparticles that were dispersed in saline solution, phosphate-buffered saline (PBS) and human serum, as determined by the inductively coupled plasma mass spectrometry (ICP-MS) method, was lower than 2 wt %. These results demonstrate the stability of the investigated nanoparticles in biologically relevant media and exclude the toxicity of Ni2+ and Zn2+ due to metal ion release, thereby opening a broad range of (bio)medical applications.
PB  - Elsevier
T2  - Ceramics International
T1  - Synthesis, characterization and in vitro evaluation of divalent ion release from stable NiFe2O4, ZnFe2O4 and core-shell ZnFe2O4@NiFe2O4 nanoparticles
VL  - 46
IS  - 3
SP  - 3528
EP  - 3533
DO  - 10.1016/j.ceramint.2019.10.068
ER  -

@article{
author = "Anđelković, Ljubica and Jeremić, Dejan and Milenković, Milica R. and Radosavljević, Jelena and Vulić, Predrag and Pavlović, Vladimir B. and Manojlović, Dragan and Nikolić, Aleksandar S.",
year = "2020",
url = "http://cer.ihtm.bg.ac.rs/handle/123456789/3145",
abstract = "A simple organic-phase synthesis process was used to produce bare NiFe2O4 and ZnFe2O4 and core-shell ZnFe2O4@NiFe2O4 ferrite nanoparticles. X-ray powder diffractograms for all investigated powders show characteristic peaks of a spinel cubic structure without a secondary phase. Transmission electron microscopy (TEM) indicated the presence of nanoparticles that are smaller than 20 nm. The release of divalent ions (Ni2+ and Zn2+) from synthesized nanoparticles that were dispersed in saline solution, phosphate-buffered saline (PBS) and human serum, as determined by the inductively coupled plasma mass spectrometry (ICP-MS) method, was lower than 2 wt %. These results demonstrate the stability of the investigated nanoparticles in biologically relevant media and exclude the toxicity of Ni2+ and Zn2+ due to metal ion release, thereby opening a broad range of (bio)medical applications.",
publisher = "Elsevier",
journal = "Ceramics International",
title = "Synthesis, characterization and in vitro evaluation of divalent ion release from stable NiFe2O4, ZnFe2O4 and core-shell ZnFe2O4@NiFe2O4 nanoparticles",
volume = "46",
number = "3",
pages = "3528-3533",
doi = "10.1016/j.ceramint.2019.10.068"
}

Anđelković L, Jeremić D, Milenković MR, Radosavljević J, Vulić P, Pavlović VB, Manojlović D, Nikolić AS. Synthesis, characterization and in vitro evaluation of divalent ion release from stable NiFe2O4, ZnFe2O4 and core-shell ZnFe2O4@NiFe2O4 nanoparticles. Ceramics International. 2020;46(3):3528-3533

Anđelković, L., Jeremić, D., Milenković, M. R., Radosavljević, J., Vulić, P., Pavlović, V. B., Manojlović, D.,& Nikolić, A. S. (2020). Synthesis, characterization and in vitro evaluation of divalent ion release from stable NiFe2O4, ZnFe2O4 and core-shell ZnFe2O4@NiFe2O4 nanoparticles.
Ceramics InternationalElsevier., 46(3), 3528-3533.
https://doi.org/10.1016/j.ceramint.2019.10.068

Anđelković Ljubica, Jeremić Dejan, Milenković Milica R., Radosavljević Jelena, Vulić Predrag, Pavlović Vladimir B., Manojlović Dragan, Nikolić Aleksandar S., "Synthesis, characterization and in vitro evaluation of divalent ion release from stable NiFe2O4, ZnFe2O4 and core-shell ZnFe2O4@NiFe2O4 nanoparticles" 46, no. 3 (2020):3528-3533,
https://doi.org/10.1016/j.ceramint.2019.10.068 .