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dc.creatorMileski, Ksenija S
dc.creatorCiric, Ana D
dc.creatorTrifunović, Snežana
dc.creatorRistic, Mihailo S
dc.creatorSoković, Marina
dc.creatorMatevski, Vlado S
dc.creatorTešević, Vele
dc.creatorJadranin, Milka
dc.creatorMarin, Petar D.
dc.creatorDzamic, Ana M
dc.date.accessioned2019-10-11T14:28:31Z
dc.date.available2017-08-16
dc.date.issued2016
dc.identifier.issn2042-6496
dc.identifier.urihttp://cer.ihtm.bg.ac.rs/handle/123456789/3130
dc.description.abstractGC-FID and GC-MS were used to determine the chemical composition of the essential oil of the aerial parts of Heracleum orphanidis Boiss. Also, the HPLC-DAD/ESI-ToF-MS profile of the methanol extracts of aerial parts and roots was determined. The main components of the essential oil were n-octanol, octyl hexanoate and n-octyl acetate, while coumarins were the most prevalent compounds in methanol extracts. An evaluation of antioxidant activity showed that the methanol and aqueous extracts of the aerial parts had the highest potential. In terms of antimicrobial activity determined by microdilution assays, the essential oil and methanol extract of the roots showed the greatest effectiveness. The colonies of Pseudomonas aeruginosa PAO1 treated with H. orphanidis samples produced less toxic pyocyanin, showed lower twitching and flagella mobility and biofilm formatting was reduced. The analyses in this study showed the considerable biological potential of H. orphanidis considering free radicals and various pathogenic strains, including the wild type of P. aeruginosa.en
dc.publisherRoyal Soc Chemistry, Cambridge
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173029/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173032/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172053/RS//
dc.rightsembargoedAccess
dc.sourceFood & Function
dc.titleHeracleum orphanidis: chemical characterisation, and comparative evaluation of antioxidant and antimicrobial activities with specific interest in the influence on Pseudomonas aeruginosa PAO1en
dc.typearticle
dc.rights.licenseARR
dcterms.abstractТешевић, Веле; Ристиц, Михаило С; Трифуновић, Снежана; Марин, Петар Д.; Јадранин, Милка; Соковиц, Марина Д.; Милески, Ксенија С; Цириц, Aна Д; Дзамиц, Aна М; Матевски, Владо С;
dc.citation.volume7
dc.citation.issue9
dc.citation.spage4061
dc.citation.epage4074
dc.citation.other7(9): 4061-4074
dc.citation.rankM21
dc.description.otherThis is peer-reviewed version of the following article: Mileski, K. S.; Ćirić, A. D.; Trifunović, S. S.; Ristić, M. S.; Soković, M. D.; Matevski, V. S.; Tešević, V. V.; Jadranin, M. B.; Marin, P. D.; Džamić, A. M. Heracleum Orphanidis: Chemical Characterisation, and Comparative Evaluation of Antioxidant and Antimicrobial Activities with Specific Interest in the Influence on Pseudomonas Aeruginosa PAO1. Food and Function 2016, 7 (9), 4061–4074. [https://doi.org/10.1039/c6fo01018k]
dc.description.other[http://cer.ihtm.bg.ac.rs/handle/123456789/1923]
dc.identifier.pmid27713984
dc.identifier.doi10.1039/c6fo01018k
dc.identifier.rcubConv_3593
dc.identifier.fulltexthttp://cer.ihtm.bg.ac.rs/bitstream/id/14118/Heracleum_orphanidis_chemical_acc_2016.pdf
dc.identifier.scopus2-s2.0-84987888552
dc.identifier.wos000384254100041
dc.type.versionacceptedVersion


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