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dc.creatorTosti, Tomislav
dc.creatorŠegan, Sandra
dc.creatorMilić, Dragana
dc.creatorRadoičić, Aleksandra D.
dc.creatorTešić, Živoslav
dc.creatorMilojković-Opsenica, Dušanka
dc.date.accessioned2019-10-04T06:04:41Z
dc.date.available2016-03-18
dc.date.issued2015
dc.identifier.issn1082-6076
dc.identifier.urihttp://cer.ihtm.bg.ac.rs/handle/123456789/3126
dc.description.abstractUnmodified silica gel in combination with two mobile phases, acetone-n-hexane and acetonitrile-dichloromethane, was used in order to evaluate the capability of normal-phase (NP) chromatography on bare silica gel in estimation of lipophilicity of some polyoxygenated steroids. Soczewinski equation coefficients were employed as a measure of lipophilicity. The R-M(0) values obtained in NP-systems were correlated with those derived by extrapolation from reversed-phase (RP) systems. In addition, retention data, i.e., lipophilicity parameters determined in NP systems were compared with logP values calculated by use of several commercial computer programs. The results showed that chromatographic parameters R-M(0), and m obtained in NP system consisted of silica gel as stationary phase and acetone-n-hexane as mobile phase, are acceptable as the measures of lipophilicity of polyoxygenated steroids. The mechanism of retention was discussed.en
dc.publisherTaylor & Francis Inc, Philadelphia
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172017/RS//
dc.rightsembargoedAccess
dc.sourceJournal of Liquid Chromatography & Related Technologies
dc.subjectpolyoxygenated steroidsen
dc.subjectstructure-retention relationshipen
dc.subjectlipophilicityen
dc.subjectnormal-phase chromatographyen
dc.subjectsilica gelen
dc.subjectcalculated lipophilicityen
dc.titleEstimation of Lipophilicity of Some Polyoxygenated Steroids by the Means of Normal-Phase Thin-Layer Chromatographyen
dc.typearticle
dc.rights.licenseARR
dcterms.abstractШеган, Сандра; Тости, Томислав; Радоичић, Aлександра Д.; Милић, Драгана; Тешић, Живослав; Милојковић-Опсеница, Душанка;
dc.citation.volume38
dc.citation.issue11
dc.citation.spage1097
dc.citation.epage1103
dc.citation.other38(11): 1097-1103
dc.citation.rankM23
dc.description.otherThis is a peer-reviewed version of the article [https://doi.org/10.1080/10826076.2015.1028287]
dc.description.otherhttp://cer.ihtm.bg.ac.rs/handle/123456789/1646
dc.identifier.doi10.1080/10826076.2015.1028287
dc.identifier.rcubConv_3334
dc.identifier.fulltexthttp://cer.ihtm.bg.ac.rs/bitstream/id/14094/tosti2015.pdf
dc.identifier.scopus2-s2.0-84929237845
dc.identifier.wos000354045900002
dc.type.versionacceptedVersion


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