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NMR Spectroscopy in the Analysis of Illegal Drugs

Samo za registrovane korisnike
2018
Autori
Vajs, Vlatka
Đorđević, Iris
Vujisić, Ljubodrag V.
Milosavljević, Slobodan
Poglavlje u monografiji (Objavljena verzija)
,
Taylor & Francis
Metapodaci
Prikaz svih podataka o dokumentu
Apstrakt
The detection of illegal drugs in various samples has been among the most fascinating objects for the practicing analytical chemist involved in forensic analysis. For centuries (until the end of the nineteenth century), drugs were almost entirely of natural origin, mostly herbal, and in some cases slightly chemically modified (e.g., through acetylation of morphine to heroin). By the development of synthetic organic chemistry (commencing at the beginning of the twentieth century), quite a few synthetic drugs designed to mimic the pharmacological effects of drugs originating from natural sources have been designed (e.g., cannabimimetic indazole derivatives or amphetamines, etc.). Detection of such synthetic drugs, named “designer drugs,” due to a large number of new substances continuously emerging on the market, is crucial. The efficacy of this analysis has become a tremendous challenge in the analytical forensic field. A development of fast identification and structural characterizatio...n is greatly facilitated by the advent of modern spectroscopic techniques, namely nuclear magnetic resonance spectroscopy (NMR) and modern mass spectrometry (MS) as well as separation techniques, such as gas and liquid chromatography (GC and LC). Nowadays, rapid strategies for chemical characterizations of illicit drugs are available.

Ključne reči:
NMR / Analysis of Illegal Drugs / Applied Spectroscopy / AB-FUBINACA / Sibutramine / Viagra / Cialis / Fake Medicine / Fake Vaccine
Izvor:
Chromatographic Techniques in the Forensic Analysis of Designer Drugs, 2018, 177-197
Izdavač:
  • Taylor & Francis
Finansiranje / projekti:
  • Bioaktivni prirodni proizvodi samoniklih, gajenih i jestivih biljaka: određivanje struktura i aktivnosti (RS-172053)

DOI: 10.1201/9781315313177

ISBN: 9781138033283

[ Google Scholar ]
URI
https://cer.ihtm.bg.ac.rs/handle/123456789/3106
Kolekcije
  • Radovi istraživača / Researchers' publications
Institucija/grupa
IHTM
TY  - CHAP
AU  - Vajs, Vlatka
AU  - Đorđević, Iris
AU  - Vujisić, Ljubodrag V.
AU  - Milosavljević, Slobodan
PY  - 2018
UR  - https://cer.ihtm.bg.ac.rs/handle/123456789/3106
AB  - The detection of illegal drugs in various samples has been among the most fascinating objects for the practicing analytical chemist involved in forensic analysis. For centuries (until the end of the nineteenth century), drugs were almost entirely of natural origin, mostly herbal, and in some cases slightly chemically modified (e.g., through acetylation of morphine to heroin). By the development of synthetic organic chemistry (commencing at the beginning of the twentieth century), quite a few synthetic drugs designed to mimic the pharmacological effects of drugs originating from natural sources have been designed (e.g., cannabimimetic indazole derivatives or amphetamines, etc.). Detection of such synthetic drugs, named “designer drugs,” due to a large number of new substances continuously emerging on the market, is crucial. The efficacy of this analysis has become a tremendous challenge in the analytical forensic field. A development of fast identification and structural characterization is greatly facilitated by the advent of modern spectroscopic techniques, namely nuclear magnetic resonance spectroscopy (NMR) and modern mass spectrometry (MS) as well as separation techniques, such as gas and liquid chromatography (GC and LC). Nowadays, rapid strategies for chemical characterizations of illicit drugs are available.
PB  - Taylor & Francis
T2  - Chromatographic Techniques in the Forensic Analysis of Designer Drugs
T1  - NMR Spectroscopy in the Analysis of Illegal Drugs
SP  - 177
EP  - 197
DO  - 10.1201/9781315313177
ER  - 
@inbook{
author = "Vajs, Vlatka and Đorđević, Iris and Vujisić, Ljubodrag V. and Milosavljević, Slobodan",
year = "2018",
abstract = "The detection of illegal drugs in various samples has been among the most fascinating objects for the practicing analytical chemist involved in forensic analysis. For centuries (until the end of the nineteenth century), drugs were almost entirely of natural origin, mostly herbal, and in some cases slightly chemically modified (e.g., through acetylation of morphine to heroin). By the development of synthetic organic chemistry (commencing at the beginning of the twentieth century), quite a few synthetic drugs designed to mimic the pharmacological effects of drugs originating from natural sources have been designed (e.g., cannabimimetic indazole derivatives or amphetamines, etc.). Detection of such synthetic drugs, named “designer drugs,” due to a large number of new substances continuously emerging on the market, is crucial. The efficacy of this analysis has become a tremendous challenge in the analytical forensic field. A development of fast identification and structural characterization is greatly facilitated by the advent of modern spectroscopic techniques, namely nuclear magnetic resonance spectroscopy (NMR) and modern mass spectrometry (MS) as well as separation techniques, such as gas and liquid chromatography (GC and LC). Nowadays, rapid strategies for chemical characterizations of illicit drugs are available.",
publisher = "Taylor & Francis",
journal = "Chromatographic Techniques in the Forensic Analysis of Designer Drugs",
booktitle = "NMR Spectroscopy in the Analysis of Illegal Drugs",
pages = "177-197",
doi = "10.1201/9781315313177"
}
Vajs, V., Đorđević, I., Vujisić, L. V.,& Milosavljević, S.. (2018). NMR Spectroscopy in the Analysis of Illegal Drugs. in Chromatographic Techniques in the Forensic Analysis of Designer Drugs
Taylor & Francis., 177-197.
https://doi.org/10.1201/9781315313177
Vajs V, Đorđević I, Vujisić LV, Milosavljević S. NMR Spectroscopy in the Analysis of Illegal Drugs. in Chromatographic Techniques in the Forensic Analysis of Designer Drugs. 2018;:177-197.
doi:10.1201/9781315313177 .
Vajs, Vlatka, Đorđević, Iris, Vujisić, Ljubodrag V., Milosavljević, Slobodan, "NMR Spectroscopy in the Analysis of Illegal Drugs" in Chromatographic Techniques in the Forensic Analysis of Designer Drugs (2018):177-197,
https://doi.org/10.1201/9781315313177 . .

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