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dc.creatorSenerovic, Lidija
dc.creatorOpsenica, Dejan
dc.creatorMoric, Ivana
dc.creatorAleksic, Ivana
dc.creatorSpasić, Marta
dc.creatorVasiljevic, Branka
dc.date.accessioned2019-09-19T12:41:25Z
dc.date.available2019-09-19T12:41:25Z
dc.date.issued2019
dc.identifier.issn2365-2675
dc.identifier.urihttp://cer.ihtm.bg.ac.rs/handle/123456789/3094
dc.description.abstractInfective diseases have become health threat of a global proportion due to appearance and spread of microorganisms resistant to majority of therapeutics currently used for their treatment. Therefore, there is a constant need for development of new antimicrobial agents, as well as novel therapeutic strategies. Quinolines and quinolones, isolated from plants, animals, and microorganisms, have demonstrated numerous biological activities such as antimicrobial, insecticidal, antiinflammatory, antiplatelet, and antitumor. For more than two centuries quinoline/quinolone moiety has been used as a scaffold for drug development and even today it represents an inexhaustible inspiration for design and development of novel semi-synthetic or synthetic agents exhibiting broad spectrum of bioactivities. The structural diversity of synthetized compounds provides high and selective activity attained through different mechanisms of action, as well as low toxicity on human cells. This review describes quinoline and quinolone derivatives with antibacterial, antifungal, anti-virulent, antiviral, and anti-parasitic activities with the focus on the last 10 years literature.sr
dc.language.isoensr
dc.publisherSpringer Naturesr
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172008/RS//sr
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/173048/RS//sr
dc.rightsrestrictedAccesssr
dc.sourceAdvances in Experimental Medicine and Biology - Advances in Microbiology, Infectious Diseases and Public Healthsr
dc.subjectAntibioticssr
dc.subjectAntifungalssr
dc.subjectAnti-parasiticssr
dc.subjectAntiviralssr
dc.subjectAnti-virulence activitysr
dc.subjectQuinoline/quinolone derivativessr
dc.titleQuinolines and Quinolones as Antibacterial, Antifungal, Antivirulence, Antiviral and Anti-parasitic Agentssr
dc.typebookPartsr
dc.rights.licenseARRsr
dcterms.abstractСенеровиц, Лидија; Васиљевиц, Бранка; Спасић, Марта; Aлексиц, Ивана; Мориц, Ивана; Опсеница, Дејан;
dc.rights.holderSpringer Nature Switzerland AG 2019sr
dc.identifier.pmid31515709
dc.identifier.doi10.1007/5584_2019_428
dc.identifier.scopus2-s2.0-85089126743
dc.type.versionpublishedVersionsr


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