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dc.creatorIzrael‑Živković, Lidija
dc.creatorBeškoski, Vladimir
dc.creatorRikalović, Milena
dc.creatorKazazić, Snježana
dc.creatorShapiro, Nicole
dc.creatorWoyke, Tanja
dc.creatorGojgić-Cvijović, Gordana
dc.creatorVrvić, Miroslav
dc.creatorMaksimović, Nela
dc.creatorKaradžić, Ivanka
dc.date.accessioned2019-07-10T10:22:55Z
dc.date.available2019-07-10T10:22:55Z
dc.date.issued2019
dc.identifier.issn1431-0651
dc.identifier.issn1433-4909
dc.identifier.urihttp://cer.ihtm.bg.ac.rs/handle/123456789/3026
dc.description.abstractThe strain Pseudomonas aeruginosa san ai, isolated from an extreme environment (industrial mineral cutting oil, pH 10), is able to survive and persist in the presence of a variety of pollutants such as heavy metals and organic chemicals. The genome of P. aeruginosa san ai is 6.98 Mbp long with a GC content of 66.08% and 6485 protein encoding genes. A large number of genes associated with proteins, responsible for microbial resistance to heavy metal ions andinvolved in catabolism of toxic aromatic organic compounds were identified. P.aeruginosa san ai is a highly cadmium-resistant strain. Proteome analysis of biomass after cadmium exposal confirmed a high tolerance to sublethal concentrations of cadmium (100mg/L), based on: extracellular biosorption, bioaccumulation, biofilm formation, controlled siderophore production and a pronounced metalloprotein synthesis. Proteins responsible for survival in osmostress conditions during exposure to elevated concentrations of cadmium (200mg/L) demonstrate a strong genetic potential of P. aeruginosa san ai for survival and adaptation. Sequencing of P. aeruginosa san ai genome provides valuable insights into the evolution and adaptation of this microbe to environmental extremes at the whole-genome level, as well as how to optimally use the strain in bioremediation of chemically polluted sites.en
dc.language.isoensr
dc.publisherSpringersr
dc.relationJGI, CSP741sr
dc.relationOffice of Science of the US Department of Energy, DE-AC02-05CH11231sr
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/43004/RS//sr
dc.rightsrestrictedAccesssr
dc.sourceExtremophilessr
dc.subjectPseudomonas aeruginosasr
dc.subjectGenomesr
dc.subjectEnvironmental isolatesr
dc.subjectChemical pollutionsr
dc.subjectCleaning polluted areassr
dc.titleHigh-quality draft genome sequence of Pseudomonas aeruginosa san ai, an environmental isolate resistant to heavy metalsen
dc.typearticlesr
dc.rights.licenseARRsr
dcterms.abstractСхапиро, Ницоле; Врвић, Мирослав М.; Wоyке, Тања; Максимовић, Нела; Казазић, Сњежана; Рикаловић, Милена; Бешкоски, Владимир; Израел‑Живковић, Лидија; Гојгић‑Цвијовић, Гордана; Караджић, Иванка;
dc.rights.holderSpringersr
dc.citation.volume23
dc.citation.issue4
dc.citation.spage399
dc.citation.epage405
dc.citation.rankM23~
dc.identifier.pmid30949775
dc.identifier.doi10.1007/s00792-019-01092-w
dc.identifier.scopus2-s2.0-85064264636
dc.identifier.wos000471018700004
dc.type.versionpublishedVersionsr


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