Приказ основних података о документу
The retention behaviour of some cholic acid derivatives on different adsorbents
dc.creator | Gaica, Sandra | |
dc.creator | Opsenica, Dejan | |
dc.creator | Šolaja, Bogdan | |
dc.creator | Tešić, Živoslav | |
dc.creator | Milojković-Opsenica, Dušanka | |
dc.date.accessioned | 2019-05-02T12:55:00Z | |
dc.date.available | 2019-05-02T12:55:00Z | |
dc.date.issued | 2002 | |
dc.identifier.issn | 0933-4173 | |
dc.identifier.uri | https://cer.ihtm.bg.ac.rs/handle/123456789/2834 | |
dc.description.abstract | The thin-layer chromatographic behavior of cholic acid and fourteen of its synthetic derivatives has been studied in six reversed-phase and three normal-phase systems. Four significantly different adsorbents were used - RP-18-silica, CN-silica, polyacrylonitrile adsorbent, and unmodified silica gel. Reversed-phase chromatography was performed with water-organic modifier (methanol, dioxane, or acetone) binary mobile phases of widely variable composition. An approximately linear relationship was obtained between R-M values and the amount of organic modifier in the mobile phases investigated. The effect of mobile-phase composition on retention has been considered and the selectivity of the chromatographic systems is also discussed. Separation mechanisms are proposed on the basis of the results obtained. A positive solvation effect was proposed as a predominant factor determining retention under normal-phase conditions whereas hydrophobic interactions of the substances with non-polar parts of the adsorbents were assumed to be predominant under reversed-phase conditions. | en |
dc.publisher | Research Inst Medicinal Plants, Budakalasz | |
dc.rights | restrictedAccess | |
dc.source | Journal of Planar Chromatography: Modern TLC / Thin Layer Chromatography | |
dc.subject | RP-18 silica | en |
dc.subject | CN-silica polyacrylonitrile adsorbent | en |
dc.subject | unmodified silica | en |
dc.subject | retention behavior | en |
dc.subject | cholic acid derivatives | en |
dc.title | The retention behaviour of some cholic acid derivatives on different adsorbents | en |
dc.type | article | |
dc.rights.license | ARR | |
dcterms.abstract | Опсеница, Дејан; Милојковић-Опсеница, Душанка; Гаица, СБ; Шолаја, Богдан A.; Тешић, Живослав Љ.; | |
dc.citation.volume | 15 | |
dc.citation.issue | 4 | |
dc.citation.spage | 299 | |
dc.citation.epage | 305 | |
dc.citation.other | 15(4): 299-305 | |
dc.citation.rank | M23 | |
dc.identifier.doi | 10.1556/JPC.15.2002.4.11 | |
dc.identifier.scopus | 2-s2.0-0036660390 | |
dc.identifier.wos | 000178677900012 | |
dc.type.version | publishedVersion |