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dc.creatorTrifunović, Snežana
dc.creatorVajs, Vlatka
dc.creatorMacura, Slobodan
dc.creatorJuranić, Nenad
dc.creatorDjarmati, Z
dc.creatorJankov, Ratko
dc.creatorMilosavljević, Slobodan
dc.date.accessioned2019-05-01T14:27:55Z
dc.date.available2019-05-01T14:27:55Z
dc.date.issued1998
dc.identifier.issn0031-9422
dc.identifier.urihttp://cer.ihtm.bg.ac.rs/handle/123456789/2807
dc.description.abstractThe isolation of two oxidation products of hyperforin from the aerial parts of Hypericum perforatum and their structure determination by means of 2D NMR methods is reported. The products had the same 1-(2-methyl-1- oxopropyl)-2,12-dioxo-3,10β-bis(3-methyl-2-butenyl)-11β-methyl-11α-(4- methyl-3-pentenyl)-5-oxatricyclo[6.3.1.0 4,8 ]-3-dodecene skeleton. In addition, one of them, with the same number of carbons as hyperforin (C 35 H 52 O 5 ), contained a 1-methyl-1-hydroxyethyl group in the 6β- position, whereas the other compound (a hemiacetal, C 32 H 46 O 5 ), presumably a degradation product of hyperforin, exhibited a 6-hydroxy function. The latter was an inseparable mixture of 6α- and 6β-hydroxy epimers undergoing (according to phase sensitive NOESY) mutual interconversion.en
dc.publisherElsevier Ltd
dc.relationMinistry for Science and Technology, Republic of Serbia
dc.rightsrestrictedAccess
dc.sourcePhytochemistry
dc.subjectHypericum perforatum
dc.subjectHypericaceae
dc.subjectsupercritical CO2
dc.subjectfractionation
dc.subjectoxidized hyperforins
dc.titleOxidation products of hyperforin from Hypericum perforatumen
dc.typearticleen
dc.rights.licenseARR
dcterms.abstractЈуранић, Ненад; Дјармати, З; Милосављевић, Слободан; Јанков, Ратко; Вајс, Влатка; Мацура, Слободан; Трифуновић, С;
dc.rights.holderElsevier
dc.citation.volume49
dc.citation.issue5
dc.citation.spage1305
dc.citation.epage1310
dc.identifier.doi10.1016/S0031-9422(97)00903-5
dc.identifier.scopus2-s2.0-0032487784
dc.identifier.wos000077125100024
dc.type.versionpublishedVersion


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