Lignans from the plant species Achillea lingulata

Abstract

Five lignans with a 2.6-diaryl-3.7-dioxabicyclo[3.3.0]octane skeleton, epieudesmin, kobusin, pinoresinol, fargesin and sesartemin, were isolated from the aerial parts and roots of Achillea lingulata. Their structures were identified by comparison of their 1 H-NMR and MS data to those in the literature. Fargesin and pinoresinol have not been isolated previously from any species of the genus Achillea.

Iz nadzemnog dela i korena biqne vrste Achillea lingulata izolovano je pet lignana 2,6-diaril-3.7-dioksabiciklo[3.3.0]oktanskog tipa. To su epieudesmin, kobusin, pinorezinol, fargezin i sezartemin. Izolovani lignani su identifikovani na osnovu identi~nosti wihovih NMR i masenih spektara sa spektrima iz literature. Fargezin i pinorezinol nisu bili do sada izolovani iz biqnih vrsta roda Achillea.