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Synthesis, biological evaluation, and modeling of a C,D-seco-taxoid
| dc.creator | Ferjančić, Zorana | |
| dc.creator | Matović, Radomir | |
| dc.creator | Čeković, Živorad | |
| dc.creator | Snyder, James P. | |
| dc.creator | Saičić, Radomir N. | |
| dc.date.accessioned | 2019-04-29T07:44:05Z | |
| dc.date.available | 2019-04-29T07:44:05Z | |
| dc.date.issued | 2005 | |
| dc.identifier.issn | 0040-4039 | |
| dc.identifier.uri | https://cer.ihtm.bg.ac.rs/handle/123456789/2770 | |
| dc.description.abstract | A C,D-seco-paclitaxel derivative 12 was prepared and tested for biological activity. The key step in the synthesis was a free radical fragmentation of the bicyclic tertiary alcohol 7 under the conditions of the hypobromite reaction. The compound 12 showed no activity in the tubulin test. (c) 2005 Elsevier Ltd. All rights reserved. | en |
| dc.publisher | Oxford : Pergamon-Elsevier Science Ltd | |
| dc.rights | restrictedAccess | |
| dc.source | Tetrahedron Letters | |
| dc.subject | taxane antitumor agents | en |
| dc.subject | radicals and radical reactions | en |
| dc.subject | medium sized rings | en |
| dc.subject | natural products | en |
| dc.subject | molecular modeling | en |
| dc.title | Synthesis, biological evaluation, and modeling of a C,D-seco-taxoid | en |
| dc.type | article | |
| dc.rights.license | ARR | |
| dcterms.abstract | Снyдер, Ј. П.; Саичић, Радомир Н.; Чековић, З.; Ферјанчић, Зорана; Матовић, Радомир; | |
| dc.citation.volume | 46 | |
| dc.citation.issue | 30 | |
| dc.citation.spage | 5049 | |
| dc.citation.epage | 5052 | |
| dc.citation.other | 46(30): 5049-5052 | |
| dc.citation.rank | M22 | |
| dc.identifier.doi | 10.1016/j.tetlet.2005.05.071 | |
| dc.identifier.scopus | 2-s2.0-20544454057 | |
| dc.identifier.wos | 000230362300027 | |
| dc.type.version | publishedVersion | en |
