Optically pure (-)-cytoxazone was synthesized, starting from methyl p-methoxycinnamate, in six steps and in 31%, overall yield. The required anti-aminoalcohol configuration was established by combining Sharpless asymmetric aminohydroxylation with the configurational inversion of the intermediate amidoalcohol via ail oxazoline. The synthesis of (+)-epi-cytoxazone is also described. (C) 2003 Elsevier Ltd. All rights reserved.
TY - JOUR
AU - Milićević, Selena
AU - Matović, Radomir
AU - Saičić, Radomir N.
PY - 2004
UR - https://cer.ihtm.bg.ac.rs/handle/123456789/2762
AB - Optically pure (-)-cytoxazone was synthesized, starting from methyl p-methoxycinnamate, in six steps and in 31%, overall yield. The required anti-aminoalcohol configuration was established by combining Sharpless asymmetric aminohydroxylation with the configurational inversion of the intermediate amidoalcohol via ail oxazoline. The synthesis of (+)-epi-cytoxazone is also described. (C) 2003 Elsevier Ltd. All rights reserved.
PB - Oxford : Pergamon-Elsevier Science Ltd
T2 - Tetrahedron Letters
T1 - Stereoselective synthesis of (-)-cytoxazone and (+)-epi-cytoxazone
VL - 45
IS - 5
SP - 955
EP - 957
DO - 10.1016/j.tetlet.2003.11.096
UR - Kon_1563
ER -
@article{
author = "Milićević, Selena and Matović, Radomir and Saičić, Radomir N.",
year = "2004",
abstract = "Optically pure (-)-cytoxazone was synthesized, starting from methyl p-methoxycinnamate, in six steps and in 31%, overall yield. The required anti-aminoalcohol configuration was established by combining Sharpless asymmetric aminohydroxylation with the configurational inversion of the intermediate amidoalcohol via ail oxazoline. The synthesis of (+)-epi-cytoxazone is also described. (C) 2003 Elsevier Ltd. All rights reserved.",
publisher = "Oxford : Pergamon-Elsevier Science Ltd",
journal = "Tetrahedron Letters",
title = "Stereoselective synthesis of (-)-cytoxazone and (+)-epi-cytoxazone",
volume = "45",
number = "5",
pages = "955-957",
doi = "10.1016/j.tetlet.2003.11.096",
url = "Kon_1563"
}
Milićević, S., Matović, R.,& Saičić, R. N.. (2004). Stereoselective synthesis of (-)-cytoxazone and (+)-epi-cytoxazone. in Tetrahedron Letters
Oxford : Pergamon-Elsevier Science Ltd., 45(5), 955-957.
https://doi.org/10.1016/j.tetlet.2003.11.096
Kon_1563
Milićević S, Matović R, Saičić RN. Stereoselective synthesis of (-)-cytoxazone and (+)-epi-cytoxazone. in Tetrahedron Letters. 2004;45(5):955-957.
doi:10.1016/j.tetlet.2003.11.096
Kon_1563 .
Milićević, Selena, Matović, Radomir, Saičić, Radomir N., "Stereoselective synthesis of (-)-cytoxazone and (+)-epi-cytoxazone" in Tetrahedron Letters, 45, no. 5 (2004):955-957,
https://doi.org/10.1016/j.tetlet.2003.11.096 .,
Kon_1563 .
, 
