Stereoselective synthesis of (-)-cytoxazone and (+)-epi-cytoxazone
Само за регистроване кориснике
2004
Чланак у часопису (Објављена верзија)
,
Elsevier
Метаподаци
Приказ свих података о документуАпстракт
Optically pure (-)-cytoxazone was synthesized, starting from methyl p-methoxycinnamate, in six steps and in 31%, overall yield. The required anti-aminoalcohol configuration was established by combining Sharpless asymmetric aminohydroxylation with the configurational inversion of the intermediate amidoalcohol via ail oxazoline. The synthesis of (+)-epi-cytoxazone is also described. (C) 2003 Elsevier Ltd. All rights reserved.
Кључне речи:
cytoxazone / asymmetric synthesis / natural products / immunosuppressive compounds / amino alcoholsИзвор:
Tetrahedron Letters, 2004, 45, 5, 955-957Издавач:
- Oxford : Pergamon-Elsevier Science Ltd
DOI: 10.1016/j.tetlet.2003.11.096
ISSN: 0040-4039
WoS: 000188380400015
Scopus: 2-s2.0-0346392218
Институција/група
IHTMTY - JOUR AU - Milićević, Selena AU - Matović, Radomir AU - Saičić, Radomir N. PY - 2004 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/2762 AB - Optically pure (-)-cytoxazone was synthesized, starting from methyl p-methoxycinnamate, in six steps and in 31%, overall yield. The required anti-aminoalcohol configuration was established by combining Sharpless asymmetric aminohydroxylation with the configurational inversion of the intermediate amidoalcohol via ail oxazoline. The synthesis of (+)-epi-cytoxazone is also described. (C) 2003 Elsevier Ltd. All rights reserved. PB - Oxford : Pergamon-Elsevier Science Ltd T2 - Tetrahedron Letters T1 - Stereoselective synthesis of (-)-cytoxazone and (+)-epi-cytoxazone VL - 45 IS - 5 SP - 955 EP - 957 DO - 10.1016/j.tetlet.2003.11.096 ER -
@article{ author = "Milićević, Selena and Matović, Radomir and Saičić, Radomir N.", year = "2004", abstract = "Optically pure (-)-cytoxazone was synthesized, starting from methyl p-methoxycinnamate, in six steps and in 31%, overall yield. The required anti-aminoalcohol configuration was established by combining Sharpless asymmetric aminohydroxylation with the configurational inversion of the intermediate amidoalcohol via ail oxazoline. The synthesis of (+)-epi-cytoxazone is also described. (C) 2003 Elsevier Ltd. All rights reserved.", publisher = "Oxford : Pergamon-Elsevier Science Ltd", journal = "Tetrahedron Letters", title = "Stereoselective synthesis of (-)-cytoxazone and (+)-epi-cytoxazone", volume = "45", number = "5", pages = "955-957", doi = "10.1016/j.tetlet.2003.11.096" }
Milićević, S., Matović, R.,& Saičić, R. N.. (2004). Stereoselective synthesis of (-)-cytoxazone and (+)-epi-cytoxazone. in Tetrahedron Letters Oxford : Pergamon-Elsevier Science Ltd., 45(5), 955-957. https://doi.org/10.1016/j.tetlet.2003.11.096
Milićević S, Matović R, Saičić RN. Stereoselective synthesis of (-)-cytoxazone and (+)-epi-cytoxazone. in Tetrahedron Letters. 2004;45(5):955-957. doi:10.1016/j.tetlet.2003.11.096 .
Milićević, Selena, Matović, Radomir, Saičić, Radomir N., "Stereoselective synthesis of (-)-cytoxazone and (+)-epi-cytoxazone" in Tetrahedron Letters, 45, no. 5 (2004):955-957, https://doi.org/10.1016/j.tetlet.2003.11.096 . .