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A New Prenylated Flavanonol from Seseli annuum Roots Showing Protective Effect on Human Lymphocytes DNA
dc.creator | Vučković, Ivan | |
dc.creator | Vajs, Vlatka | |
dc.creator | Stanković, Miroslava | |
dc.creator | Tešević, Vele | |
dc.creator | Milosavljević, Slobodan | |
dc.date.accessioned | 2019-04-27T10:24:16Z | |
dc.date.available | 2019-04-27T10:24:16Z | |
dc.date.issued | 2010 | |
dc.identifier.issn | 1612-1872 | |
dc.identifier.uri | https://cer.ihtm.bg.ac.rs/handle/123456789/2732 | |
dc.description.abstract | A new prenylated flavanonol named seselinonol (1) was isolated from the roots of Seseli annuum, together with the well-known biologically active polyacetylenes falcarinol (2) and falcarindiol (3), and the prenylated furanocoumarin phellopterin (4). Its structure was elucidated by extensive spectroscopic analysis, including HR-ESI-MS, ID- and 2D-NMR. Seselinonol and phellopterin were tested for in vitro protective effect on chromosome aberrations in peripheral human lymphocytes using cytochalasin-B blocked micronucleus (CBMN) assay. The new compound exerted a beneficial effect by decreasing DNA damage of human lymphocytes. | en |
dc.publisher | Wiley-V C H Verlag Gmbh, Weinheim | |
dc.relation | info:eu-repo/grantAgreement/MESTD/MPN2006-2010/142053/RS// | |
dc.rights | restrictedAccess | |
dc.source | Chemistry and Biodiversity | |
dc.title | A New Prenylated Flavanonol from Seseli annuum Roots Showing Protective Effect on Human Lymphocytes DNA | en |
dc.type | article | |
dc.rights.license | ARR | |
dc.citation.volume | 7 | |
dc.citation.issue | 3 | |
dc.citation.spage | 698 | |
dc.citation.epage | 704 | |
dc.citation.other | 7(3): 698-704 | |
dc.citation.rank | M22 | |
dc.identifier.pmid | 20232332 | |
dc.identifier.doi | 10.1002/cbdv.200900067 | |
dc.identifier.scopus | 2-s2.0-77949728574 | |
dc.identifier.wos | 000276059600015 | |
dc.type.version | publishedVersion | en |