In this paper is described a synthetic pathway to the modified 5, 10:8, 14-bisfragmentation cholestene derivatives 10, 11 and 12, which involves introduction of the Δ8(14)-double bond and 5α-hydroxyl group in the cholestane molecule and subsequent cleavage of the olefinic C(8)-C(14) bond (with ruthenium tetroxide) and C(5)-C(10) bond (with mercuric oxide/iodine or lead tetracetate/iodine).
Keywords:
Lactones / Acetates / secosteroidal macrocycles
Source:
Journal of the Serbian Chemical Society, 1996, 61, 11, 941-946
TY - JOUR
AU - Mihailović, Milhailo Lj.
AU - Pavlović, Vladimir D.
AU - Bondarenko-Gheorghiu, Lidija
AU - Krstić, Natalija
AU - Dabović, Milan
AU - Lorenc, Ljubinka
PY - 1996
UR - https://cer.ihtm.bg.ac.rs/handle/123456789/2708
AB - In this paper is described a synthetic pathway to the modified 5, 10:8, 14-bisfragmentation cholestene derivatives 10, 11 and 12, which involves introduction of the Δ8(14)-double bond and 5α-hydroxyl group in the cholestane molecule and subsequent cleavage of the olefinic C(8)-C(14) bond (with ruthenium tetroxide) and C(5)-C(10) bond (with mercuric oxide/iodine or lead tetracetate/iodine).
PB - Serbian Chemical Society
T2 - Journal of the Serbian Chemical Society
T1 - Synthesis of modified 5,10:8,14-bisfragmentation cholestane derivatives
VL - 61
IS - 11
SP - 941
EP - 946
UR - https://hdl.handle.net/21.15107/rcub_cer_2708
ER -
@article{
author = "Mihailović, Milhailo Lj. and Pavlović, Vladimir D. and Bondarenko-Gheorghiu, Lidija and Krstić, Natalija and Dabović, Milan and Lorenc, Ljubinka",
year = "1996",
abstract = "In this paper is described a synthetic pathway to the modified 5, 10:8, 14-bisfragmentation cholestene derivatives 10, 11 and 12, which involves introduction of the Δ8(14)-double bond and 5α-hydroxyl group in the cholestane molecule and subsequent cleavage of the olefinic C(8)-C(14) bond (with ruthenium tetroxide) and C(5)-C(10) bond (with mercuric oxide/iodine or lead tetracetate/iodine).",
publisher = "Serbian Chemical Society",
journal = "Journal of the Serbian Chemical Society",
title = "Synthesis of modified 5,10:8,14-bisfragmentation cholestane derivatives",
volume = "61",
number = "11",
pages = "941-946",
url = "https://hdl.handle.net/21.15107/rcub_cer_2708"
}
Mihailović, M. Lj., Pavlović, V. D., Bondarenko-Gheorghiu, L., Krstić, N., Dabović, M.,& Lorenc, L.. (1996). Synthesis of modified 5,10:8,14-bisfragmentation cholestane derivatives. in Journal of the Serbian Chemical Society
Serbian Chemical Society., 61(11), 941-946.
https://hdl.handle.net/21.15107/rcub_cer_2708
Mihailović ML, Pavlović VD, Bondarenko-Gheorghiu L, Krstić N, Dabović M, Lorenc L. Synthesis of modified 5,10:8,14-bisfragmentation cholestane derivatives. in Journal of the Serbian Chemical Society. 1996;61(11):941-946.
https://hdl.handle.net/21.15107/rcub_cer_2708 .
Mihailović, Milhailo Lj., Pavlović, Vladimir D., Bondarenko-Gheorghiu, Lidija, Krstić, Natalija, Dabović, Milan, Lorenc, Ljubinka, "Synthesis of modified 5,10:8,14-bisfragmentation cholestane derivatives" in Journal of the Serbian Chemical Society, 61, no. 11 (1996):941-946,
https://hdl.handle.net/21.15107/rcub_cer_2708 .
