Synthesis of modified 5,10:8,14-bisfragmentation cholestane derivatives
AuthorsMihailović, Mihailo Lj.
Pavlović, Vladimir D.
Article (Published version)
MetadataShow full item record
In this paper is described a synthetic pathway to the modified 5, 10:8, 14-bisfragmentation cholestene derivatives 10, 11 and 12, which involves introduction of the Δ8(14)-double bond and 5α-hydroxyl group in the cholestane molecule and subsequent cleavage of the olefinic C(8)-C(14) bond (with ruthenium tetroxide) and C(5)-C(10) bond (with mercuric oxide/iodine or lead tetracetate/iodine).
Keywords:Lactones / Acetates / secosteroidal macrocycles
Source:Journal of the Serbian Chemical Society, 1996, 61, 11, 941-946
- Serbian Chemical Society