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Morphological characteristics of anaphoretically obtained hydroxyapatite/titanium dioxide coatings

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2018
XXYuCorr-p142 (6.257Mb)
Authors
Pantović Pavlović, Marijana
Eraković, Sanja
Pavlović, Miroslav M.
Stevanović, Jasmina
Panić, Vladimir
Conference object (Published version)
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Abstract
Hydroxyapatite (HAP, Ca10(PO4)6(OH)2) is a main mineral constituent of hard tissue, making up 93% of human bone with stoichiometric Ca/P ratio of 1.667. It is widely used in medical applications such as tissue engineering, drug delivery and bone tissue repair. Nowadays, to enhance biocompatibility of the metallic implants, mostly based on titanium, the surface modification by deposition of bioactive and biocompatible HAP coatings has been proposed. The electrophoretic deposition (EPD) is a versatile and cost-effective technique for fabricating advanced HAP coatings. In this study, in situ synthesis of HAP/TiO2 coating on titanium was prepared on titanium substrates via anaphoretic EPD of HAP and simultaneous anodization of Ti to strengthen the biocompatible composite coating. The prepared coatings were characterized using optical miscroscope, scanning electron microscopy, Fourier transform infrared spectroscopy and X-ray diffraction. It was found that controlling the depositi...on conditions it is possible to obtain HAP/anodized titanium dioxide coatings of variable thickness and porosity. Since smaller size HAP crystals with highly porous structure shows very high binding ability to various biomolecules, our coating is of excellent coverage and compactness. The obtained coating appears promising candidate for further biomedical applications with appropriate morphology for adhesion of osteoblasts.

Keywords:
titanium dioxide coatings / Morphological characteristics / hydroxyapatite / hard tissue / tissue engineering / drug delivery / bone / bone tissue repair / biocompatibility / HAP coatings / EPD / optical miscroscope / electron microscopy / Fourier transform infrared spectroscopy / X-ray diffraction / adhesion of osteoblasts
Source:
Stecište nauke i prakse u oblastima korozije, zaštite materijala i životne sredine - XX YuCorr [Jugoslovenska korozija] Međunarodna konferencija - knjiga radova/ Meeting Point of the Science and Practice in the Fields of Corrosion, Materials and Environmental Protection - XX YuCorr International Conference - proceedings [May 21-24, 2018, Tara Mountain, Serbia], 2018, 142-142
Publisher:
  • Beograd : Naučna ustanova za hemiju, tehnologiju i metalurgiju, Institut od nacionalnog značaja
  • Beograd : Udruženje inženjera Srbije za koroziju i zaštitu materijala ( UISKOZAM )

ISBN: 978-86-82343-26-4

[ Google Scholar ]
URI
http://cer.ihtm.bg.ac.rs/handle/123456789/2652
Collections
  • Radovi istraživača / Researchers' publications
Institution
IHTM
TY  - CONF
AU  - Pantović Pavlović, Marijana
AU  - Eraković, Sanja
AU  - Pavlović, Miroslav M.
AU  - Stevanović, Jasmina
AU  - Panić, Vladimir
PY  - 2018
UR  - http://cer.ihtm.bg.ac.rs/handle/123456789/2652
AB  - Hydroxyapatite (HAP, Ca10(PO4)6(OH)2) is a main mineral constituent of hard tissue, making up
93% of human bone with stoichiometric Ca/P ratio of 1.667. It is widely used in medical applications
such as tissue engineering, drug delivery and bone tissue repair. Nowadays, to enhance
biocompatibility of the metallic implants, mostly based on titanium, the surface modification by
deposition of bioactive and biocompatible HAP coatings has been proposed. The electrophoretic
deposition (EPD) is a versatile and cost-effective technique for fabricating advanced HAP coatings.
In this study, in situ synthesis of HAP/TiO2 coating on titanium was prepared on titanium substrates
via anaphoretic EPD of HAP and simultaneous anodization of Ti to strengthen the biocompatible
composite coating. The prepared coatings were characterized using optical miscroscope, scanning
electron microscopy, Fourier transform infrared spectroscopy and X-ray diffraction. It was found
that controlling the deposition conditions it is possible to obtain HAP/anodized titanium dioxide
coatings of variable thickness and porosity. Since smaller size HAP crystals with highly porous
structure shows very high binding ability to various biomolecules, our coating is of excellent coverage
and compactness. The obtained coating appears promising candidate for further biomedical
applications with appropriate morphology for adhesion of osteoblasts.
PB  - Beograd : Naučna ustanova za hemiju, tehnologiju i metalurgiju, Institut od nacionalnog značaja
PB  - Beograd : Udruženje inženjera Srbije za koroziju i zaštitu materijala  ( UISKOZAM )
C3  - Stecište nauke i prakse u oblastima korozije, zaštite materijala i životne sredine - XX YuCorr [Jugoslovenska korozija] Međunarodna konferencija - knjiga radova/ Meeting Point of the Science and Practice in the Fields of Corrosion, Materials and Environmental Protection - XX YuCorr International Conference - proceedings [May 21-24, 2018, Tara Mountain, Serbia]
T1  - Morphological characteristics of anaphoretically obtained hydroxyapatite/titanium dioxide coatings
SP  - 142
EP  - 142
ER  - 
@conference{
author = "Pantović Pavlović, Marijana and Eraković, Sanja and Pavlović, Miroslav M. and Stevanović, Jasmina and Panić, Vladimir",
year = "2018",
url = "http://cer.ihtm.bg.ac.rs/handle/123456789/2652",
abstract = "Hydroxyapatite (HAP, Ca10(PO4)6(OH)2) is a main mineral constituent of hard tissue, making up
93% of human bone with stoichiometric Ca/P ratio of 1.667. It is widely used in medical applications
such as tissue engineering, drug delivery and bone tissue repair. Nowadays, to enhance
biocompatibility of the metallic implants, mostly based on titanium, the surface modification by
deposition of bioactive and biocompatible HAP coatings has been proposed. The electrophoretic
deposition (EPD) is a versatile and cost-effective technique for fabricating advanced HAP coatings.
In this study, in situ synthesis of HAP/TiO2 coating on titanium was prepared on titanium substrates
via anaphoretic EPD of HAP and simultaneous anodization of Ti to strengthen the biocompatible
composite coating. The prepared coatings were characterized using optical miscroscope, scanning
electron microscopy, Fourier transform infrared spectroscopy and X-ray diffraction. It was found
that controlling the deposition conditions it is possible to obtain HAP/anodized titanium dioxide
coatings of variable thickness and porosity. Since smaller size HAP crystals with highly porous
structure shows very high binding ability to various biomolecules, our coating is of excellent coverage
and compactness. The obtained coating appears promising candidate for further biomedical
applications with appropriate morphology for adhesion of osteoblasts.",
publisher = "Beograd : Naučna ustanova za hemiju, tehnologiju i metalurgiju, Institut od nacionalnog značaja, Beograd : Udruženje inženjera Srbije za koroziju i zaštitu materijala  ( UISKOZAM )",
journal = "Stecište nauke i prakse u oblastima korozije, zaštite materijala i životne sredine - XX YuCorr [Jugoslovenska korozija] Međunarodna konferencija - knjiga radova/ Meeting Point of the Science and Practice in the Fields of Corrosion, Materials and Environmental Protection - XX YuCorr International Conference - proceedings [May 21-24, 2018, Tara Mountain, Serbia]",
title = "Morphological characteristics of anaphoretically obtained hydroxyapatite/titanium dioxide coatings",
pages = "142-142"
}
Pantović Pavlović M, Eraković S, Pavlović MM, Stevanović J, Panić V. Morphological characteristics of anaphoretically obtained hydroxyapatite/titanium dioxide coatings. Stecište nauke i prakse u oblastima korozije, zaštite materijala i životne sredine - XX YuCorr [Jugoslovenska korozija] Međunarodna konferencija - knjiga radova/ Meeting Point of the Science and Practice in the Fields of Corrosion, Materials and Environmental Protection - XX YuCorr International Conference - proceedings [May 21-24, 2018, Tara Mountain, Serbia]. 2018;:142-142
Pantović Pavlović, M., Eraković, S., Pavlović, M. M., Stevanović, J.,& Panić, V. (2018). Morphological characteristics of anaphoretically obtained hydroxyapatite/titanium dioxide coatings.
Stecište nauke i prakse u oblastima korozije, zaštite materijala i životne sredine - XX YuCorr [Jugoslovenska korozija] Međunarodna konferencija - knjiga radova/ Meeting Point of the Science and Practice in the Fields of Corrosion, Materials and Environmental Protection - XX YuCorr International Conference - proceedings [May 21-24, 2018, Tara Mountain, Serbia]Beograd : Udruženje inženjera Srbije za koroziju i zaštitu materijala  ( UISKOZAM )., 142-142.
Pantović Pavlović Marijana, Eraković Sanja, Pavlović Miroslav M., Stevanović Jasmina, Panić Vladimir, "Morphological characteristics of anaphoretically obtained hydroxyapatite/titanium dioxide coatings" (2018):142-142

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