Antimicrobial performance of silver nanoparticles supported by functionalized hydroxyapatite with 5-aminosalycile acid was tested against Gram-negative bacteria E. coli, Gram-positive bacteria S. aureus and yeast C. albicans. Thorough characterization of materials (electron microscopy, nitrogen adsorption desorption isotherms, diffuse reflectance spectroscopy) followed each step during the course of nanocomposite preparation. Synthesized powder consists of rod-like hydroxyapatite particles (40-60 x 10-20 nm, length x diameter) decorated with nano-sized spherical silver particles whose content in nanocomposite was found to be 1.9 wt.-%. Concentration- and time-dependent bacterial reduction data indicated that use of silver nanoparticles even at concentration as low as 1 mu g mL(-1) lead to complete reduction of both bacteria (E. coli and S. aureus). On the other hand, non-toxic behavior of nanocomposite in broad concentration range (0.05-2.0 mg mL(-1)) was found towards C albicans. Succ...essful inactivation of E. coli and S. aureus in five repeated cycles proved that synthesized nanocomposite can perform under long-run working conditions.
TY - JOUR
AU - Lazić, Vesna
AU - Smiciklas, Ivana
AU - Markovic, Jelena
AU - Lončarević, Davor
AU - Dostanić, Jasmina
AU - Ahrenkiel, Scott Phillip
AU - Nedeljković, Jovan M.
PY - 2018
UR - http://cer.ihtm.bg.ac.rs/handle/123456789/2455
AB - Antimicrobial performance of silver nanoparticles supported by functionalized hydroxyapatite with 5-aminosalycile acid was tested against Gram-negative bacteria E. coli, Gram-positive bacteria S. aureus and yeast C. albicans. Thorough characterization of materials (electron microscopy, nitrogen adsorption desorption isotherms, diffuse reflectance spectroscopy) followed each step during the course of nanocomposite preparation. Synthesized powder consists of rod-like hydroxyapatite particles (40-60 x 10-20 nm, length x diameter) decorated with nano-sized spherical silver particles whose content in nanocomposite was found to be 1.9 wt.-%. Concentration- and time-dependent bacterial reduction data indicated that use of silver nanoparticles even at concentration as low as 1 mu g mL(-1) lead to complete reduction of both bacteria (E. coli and S. aureus). On the other hand, non-toxic behavior of nanocomposite in broad concentration range (0.05-2.0 mg mL(-1)) was found towards C albicans. Successful inactivation of E. coli and S. aureus in five repeated cycles proved that synthesized nanocomposite can perform under long-run working conditions.
PB - Pergamon-Elsevier Science Ltd, Oxford
T2 - Vacuum
T1 - Antibacterial ability of supported silver nanoparticles by functionalized hydroxyapatite with 5-aminosalicylic acid
VL - 148
SP - 62
EP - 68
DO - 10.1016/j.vacuum.2017.10.039
ER -
@article{
author = "Lazić, Vesna and Smiciklas, Ivana and Markovic, Jelena and Lončarević, Davor and Dostanić, Jasmina and Ahrenkiel, Scott Phillip and Nedeljković, Jovan M.",
year = "2018",
url = "http://cer.ihtm.bg.ac.rs/handle/123456789/2455",
abstract = "Antimicrobial performance of silver nanoparticles supported by functionalized hydroxyapatite with 5-aminosalycile acid was tested against Gram-negative bacteria E. coli, Gram-positive bacteria S. aureus and yeast C. albicans. Thorough characterization of materials (electron microscopy, nitrogen adsorption desorption isotherms, diffuse reflectance spectroscopy) followed each step during the course of nanocomposite preparation. Synthesized powder consists of rod-like hydroxyapatite particles (40-60 x 10-20 nm, length x diameter) decorated with nano-sized spherical silver particles whose content in nanocomposite was found to be 1.9 wt.-%. Concentration- and time-dependent bacterial reduction data indicated that use of silver nanoparticles even at concentration as low as 1 mu g mL(-1) lead to complete reduction of both bacteria (E. coli and S. aureus). On the other hand, non-toxic behavior of nanocomposite in broad concentration range (0.05-2.0 mg mL(-1)) was found towards C albicans. Successful inactivation of E. coli and S. aureus in five repeated cycles proved that synthesized nanocomposite can perform under long-run working conditions.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Vacuum",
title = "Antibacterial ability of supported silver nanoparticles by functionalized hydroxyapatite with 5-aminosalicylic acid",
volume = "148",
pages = "62-68",
doi = "10.1016/j.vacuum.2017.10.039"
}
Lazić, V., Smiciklas, I., Markovic, J., Lončarević, D., Dostanić, J., Ahrenkiel, S. P.,& Nedeljković, J. M. (2018). Antibacterial ability of supported silver nanoparticles by functionalized hydroxyapatite with 5-aminosalicylic acid.
Vacuum
Pergamon-Elsevier Science Ltd, Oxford., 148, 62-68.
https://doi.org/10.1016/j.vacuum.2017.10.039
Lazić V, Smiciklas I, Markovic J, Lončarević D, Dostanić J, Ahrenkiel SP, Nedeljković JM. Antibacterial ability of supported silver nanoparticles by functionalized hydroxyapatite with 5-aminosalicylic acid. Vacuum. 2018;148:62-68
Lazić Vesna, Smiciklas Ivana, Markovic Jelena, Lončarević Davor, Dostanić Jasmina, Ahrenkiel Scott Phillip, Nedeljković Jovan M., "Antibacterial ability of supported silver nanoparticles by functionalized hydroxyapatite with 5-aminosalicylic acid" Vacuum, 148 (2018):62-68,
https://doi.org/10.1016/j.vacuum.2017.10.039 .
