Improving stability of cerium oxide nanoparticles by microbial polysaccharides coating

2018
Authors
Milenkovic, IvanaRadotić, Ksenija

Matović, Branko

Prekajski, Marija

Živković, Ljiljana S.

Jakovljević, Dragica

Gojgić-Cvijović, Gordana

Beškoski, Vladimir

Article (Published version)
Metadata
Show full item recordAbstract
Cerium oxide (CeO2) nanoparticles (CONPs) are interesting biomaterials with various applications in biomedicine, cosmetics and the pharmaceutical industry, but with limited practical application because of their low stability in aqueous media. The aim of this study was to obtain CONPs with increased stability by coating the particles. Microbial exopolysaccharides (levan, pullulan) and glucose were used to prepare CONPs under different synthesis conditions. Coating was attempted by adding the carbohydrates during (direct coating) or after (subsequent coating) the synthesis of CONPs. The obtained nanoparticles were characterized by X-Ray diffraction analysis, Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The suspension stability of the uncoated and coated CONPs in aqueous media was evaluated by measuring the hydrodynamic size, zeta potential and turbidity. The FT-IR spectra revealed the differences between ...coated CONPs and showed the success of subsequent coating with carbohydrates. Coating with carbohydrates improved the stability the CONP suspension by decreasing the size of aggregated particles. The suspensions of levan- and glucose-coated CONPs had the best stability. In this study, CONPs were prepared using non-toxic materials, which were completely environmentally friendly. The obtained results open new horizons for CONP synthesis, improving their biological applications.
Keywords:
biomaterial / CeO2 / glucose / levan / pullulan / surfacesSource:
Journal of the Serbian Chemical Society, 2018, 83, 6, 745-757Publisher:
- Serbian Chemical Soc, Belgrade
Funding / projects:
- Synthesis, processing and characterization of nanostructured materials for application in the field of energy, mechanical engineering, environmental protection and biomedicine (RS-45012)
- Simultaneous Bioremediation and Soilification of Degraded Areas to Preserve Natural Resources of Biologically Active Substances, and Development and Production of Biomaterials and Dietetic Products (RS-43004)
DOI: 10.2298/JSC171205031M
ISSN: 0352-5139
WoS: 000437822100007
Scopus: 2-s2.0-85049409163
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Institution/Community
IHTMTY - JOUR AU - Milenkovic, Ivana AU - Radotić, Ksenija AU - Matović, Branko AU - Prekajski, Marija AU - Živković, Ljiljana S. AU - Jakovljević, Dragica AU - Gojgić-Cvijović, Gordana AU - Beškoski, Vladimir PY - 2018 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/2447 AB - Cerium oxide (CeO2) nanoparticles (CONPs) are interesting biomaterials with various applications in biomedicine, cosmetics and the pharmaceutical industry, but with limited practical application because of their low stability in aqueous media. The aim of this study was to obtain CONPs with increased stability by coating the particles. Microbial exopolysaccharides (levan, pullulan) and glucose were used to prepare CONPs under different synthesis conditions. Coating was attempted by adding the carbohydrates during (direct coating) or after (subsequent coating) the synthesis of CONPs. The obtained nanoparticles were characterized by X-Ray diffraction analysis, Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The suspension stability of the uncoated and coated CONPs in aqueous media was evaluated by measuring the hydrodynamic size, zeta potential and turbidity. The FT-IR spectra revealed the differences between coated CONPs and showed the success of subsequent coating with carbohydrates. Coating with carbohydrates improved the stability the CONP suspension by decreasing the size of aggregated particles. The suspensions of levan- and glucose-coated CONPs had the best stability. In this study, CONPs were prepared using non-toxic materials, which were completely environmentally friendly. The obtained results open new horizons for CONP synthesis, improving their biological applications. PB - Serbian Chemical Soc, Belgrade T2 - Journal of the Serbian Chemical Society T1 - Improving stability of cerium oxide nanoparticles by microbial polysaccharides coating VL - 83 IS - 6 SP - 745 EP - 757 DO - 10.2298/JSC171205031M ER -
@article{ author = "Milenkovic, Ivana and Radotić, Ksenija and Matović, Branko and Prekajski, Marija and Živković, Ljiljana S. and Jakovljević, Dragica and Gojgić-Cvijović, Gordana and Beškoski, Vladimir", year = "2018", abstract = "Cerium oxide (CeO2) nanoparticles (CONPs) are interesting biomaterials with various applications in biomedicine, cosmetics and the pharmaceutical industry, but with limited practical application because of their low stability in aqueous media. The aim of this study was to obtain CONPs with increased stability by coating the particles. Microbial exopolysaccharides (levan, pullulan) and glucose were used to prepare CONPs under different synthesis conditions. Coating was attempted by adding the carbohydrates during (direct coating) or after (subsequent coating) the synthesis of CONPs. The obtained nanoparticles were characterized by X-Ray diffraction analysis, Fourier transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The suspension stability of the uncoated and coated CONPs in aqueous media was evaluated by measuring the hydrodynamic size, zeta potential and turbidity. The FT-IR spectra revealed the differences between coated CONPs and showed the success of subsequent coating with carbohydrates. Coating with carbohydrates improved the stability the CONP suspension by decreasing the size of aggregated particles. The suspensions of levan- and glucose-coated CONPs had the best stability. In this study, CONPs were prepared using non-toxic materials, which were completely environmentally friendly. The obtained results open new horizons for CONP synthesis, improving their biological applications.", publisher = "Serbian Chemical Soc, Belgrade", journal = "Journal of the Serbian Chemical Society", title = "Improving stability of cerium oxide nanoparticles by microbial polysaccharides coating", volume = "83", number = "6", pages = "745-757", doi = "10.2298/JSC171205031M" }
Milenkovic, I., Radotić, K., Matović, B., Prekajski, M., Živković, L. S., Jakovljević, D., Gojgić-Cvijović, G.,& Beškoski, V.. (2018). Improving stability of cerium oxide nanoparticles by microbial polysaccharides coating. in Journal of the Serbian Chemical Society Serbian Chemical Soc, Belgrade., 83(6), 745-757. https://doi.org/10.2298/JSC171205031M
Milenkovic I, Radotić K, Matović B, Prekajski M, Živković LS, Jakovljević D, Gojgić-Cvijović G, Beškoski V. Improving stability of cerium oxide nanoparticles by microbial polysaccharides coating. in Journal of the Serbian Chemical Society. 2018;83(6):745-757. doi:10.2298/JSC171205031M .
Milenkovic, Ivana, Radotić, Ksenija, Matović, Branko, Prekajski, Marija, Živković, Ljiljana S., Jakovljević, Dragica, Gojgić-Cvijović, Gordana, Beškoski, Vladimir, "Improving stability of cerium oxide nanoparticles by microbial polysaccharides coating" in Journal of the Serbian Chemical Society, 83, no. 6 (2018):745-757, https://doi.org/10.2298/JSC171205031M . .