We investigate the stochastic sensor response in equilibrium, taking into account competitive adsorption and mass transfer of analyte particles in a microfluidic biosensor chamber. After presentation of the stochastic model, we perform the analysis of the equilibrium response expected value as a function of the sensing area and the competitor molecules concentrations. By comparison with the deterministic value of the sensor response, the limits of applicability of the deterministic approach are investigated. The results of the presented analysis enable better interpretation of measurement results obtained by using sensors with micro/nanoscale sensing surface, as well as optimization of their design and operating conditions.
Keywords:
Biosensor / stochastic time response / deterministic time response / competitive adsorption
TY - CONF
AU - Jokić, Ivana
AU - Đurić, Zoran G.
AU - Radulović, Katarina
AU - Frantlović, Miloš
PY - 2018
UR - http://cer.ihtm.bg.ac.rs/handle/123456789/2419
AB - We investigate the stochastic sensor response in equilibrium, taking into account competitive adsorption and mass transfer of analyte particles in a microfluidic biosensor chamber. After presentation of the stochastic model, we perform the analysis of the equilibrium response expected value as a function of the sensing area and the competitor molecules concentrations. By comparison with the deterministic value of the sensor response, the limits of applicability of the deterministic approach are investigated. The results of the presented analysis enable better interpretation of measurement results obtained by using sensors with micro/nanoscale sensing surface, as well as optimization of their design and operating conditions.
C3 - Materials Today-Proceedings
T1 - Deterministic versus Stochastic Analysis of Competitive Adsorption in Equilibrium in Microfluidic Biosensors
VL - 5
IS - 8
SP - 16006
EP - 16011
DO - 10.1016/j.matpr.2018.05.045
ER -
@conference{
author = "Jokić, Ivana and Đurić, Zoran G. and Radulović, Katarina and Frantlović, Miloš",
year = "2018",
url = "http://cer.ihtm.bg.ac.rs/handle/123456789/2419",
abstract = "We investigate the stochastic sensor response in equilibrium, taking into account competitive adsorption and mass transfer of analyte particles in a microfluidic biosensor chamber. After presentation of the stochastic model, we perform the analysis of the equilibrium response expected value as a function of the sensing area and the competitor molecules concentrations. By comparison with the deterministic value of the sensor response, the limits of applicability of the deterministic approach are investigated. The results of the presented analysis enable better interpretation of measurement results obtained by using sensors with micro/nanoscale sensing surface, as well as optimization of their design and operating conditions.",
journal = "Materials Today-Proceedings",
title = "Deterministic versus Stochastic Analysis of Competitive Adsorption in Equilibrium in Microfluidic Biosensors",
volume = "5",
number = "8",
pages = "16006-16011",
doi = "10.1016/j.matpr.2018.05.045"
}
Jokić, I., Đurić, Z. G., Radulović, K.,& Frantlović, M. (2018). Deterministic versus Stochastic Analysis of Competitive Adsorption in Equilibrium in Microfluidic Biosensors.
Materials Today-Proceedings, 5(8), 16006-16011.
https://doi.org/10.1016/j.matpr.2018.05.045
Jokić I, Đurić ZG, Radulović K, Frantlović M. Deterministic versus Stochastic Analysis of Competitive Adsorption in Equilibrium in Microfluidic Biosensors. Materials Today-Proceedings. 2018;5(8):16006-16011
Jokić Ivana, Đurić Zoran G., Radulović Katarina, Frantlović Miloš, "Deterministic versus Stochastic Analysis of Competitive Adsorption in Equilibrium in Microfluidic Biosensors" Materials Today-Proceedings, 5, no. 8 (2018):16006-16011,
https://doi.org/10.1016/j.matpr.2018.05.045 .
