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Deterministic versus Stochastic Analysis of Competitive Adsorption in Equilibrium in Microfluidic Biosensors

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2018
Authors
Jokić, Ivana
Đurić, Zoran G.
Radulović, Katarina
Frantlović, Miloš
Conference object (Published version)
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Abstract
We investigate the stochastic sensor response in equilibrium, taking into account competitive adsorption and mass transfer of analyte particles in a microfluidic biosensor chamber. After presentation of the stochastic model, we perform the analysis of the equilibrium response expected value as a function of the sensing area and the competitor molecules concentrations. By comparison with the deterministic value of the sensor response, the limits of applicability of the deterministic approach are investigated. The results of the presented analysis enable better interpretation of measurement results obtained by using sensors with micro/nanoscale sensing surface, as well as optimization of their design and operating conditions.
Keywords:
Biosensor / stochastic time response / deterministic time response / competitive adsorption
Source:
Materials Today-Proceedings, 2018, 5, 8, 16006-16011
Projects:
  • Micro- Nanosystems and Sensors for Electric Power and Process Industry and Environmental Protection (RS-32008)
  • Serbian Academy of Sciences and Arts, Project F-150

DOI: 10.1016/j.matpr.2018.05.045

ISSN: 2214-7853

WoS: 000441006800008

Scopus: 2-s2.0-85056510161
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URI
http://cer.ihtm.bg.ac.rs/handle/123456789/2419
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