New aurone epoxide and auronolignan from the heartwood of Cotinus coggygria Scop
Samo za registrovane korisnike
2018
Autori
Novaković, MiroslavĐorđević, Iris
Todorović, Nina
Trifunovic, S.
Anđelković, Boban D.
Mandić, Boris
Jadranin, Milka
Vučković, Ivan
Vajs, Vlatka
Milosavljević, Slobodan
Tešević, Vele
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
New aurone epoxide, 2,10-oxy-10-methoxysulfuretin (14), and new auronolignan (15), named cotinignan A, were isolated by silica gel column and semipreparative HPLC chromatography from the methylene chloride/methanol extract of Cotinus coggygria Scop. heartwood. In addition, thirteen known secondary metabolites namely sulfuretin, 2,3-trans-fustin, fisetin, butin, butein, taxifolin, eriodictyol, 3',5,5',7–tetrahydroxyflavanone, 3',4',7-trihydroxyflavone, 3-O-methyl-2,3-trans-fustin, 3-O-galloyl-2,3-trans-fustin, β-resorcylic acid and 3-O-β-sitosterol glucoside were isolated as well. Their structures were elucidated by 1D and 2D NMR, HR-ESI-MS, IR and UV. Ten out of eleven isolated flavonoids possess 7, 3' and 4' hydroxy groups. These structural features could be considered as chemotaxonomic characteristic of flavonoids from C. coggygria. Cotinignan A (15) represents new subclass of secondary metabolites - auronolignans. (Figure presented.).
Ključne reči:
cotinignan A / Cotinus coggygria Scop / flavonoids / NMR / semipreparative HPLCIzvor:
Natural Product Research, 2018, 33, 19, 2837-2844Izdavač:
- Taylor and Francis Ltd.
Finansiranje / projekti:
- Bioaktivni prirodni proizvodi samoniklih, gajenih i jestivih biljaka: određivanje struktura i aktivnosti (RS-MESTD-Basic Research (BR or ON)-172053)
Napomena:
- Supplementary material: https://cer.ihtm.bg.ac.rs/handle/123456789/4447
Povezane informacije:
- Povezani sadržaj
https://cer.ihtm.bg.ac.rs/handle/123456789/4447
DOI: 10.1080/14786419.2018.1508141
ISSN: 1478-6419
PubMed: 30513208
WoS: 000478893800017
Scopus: 2-s2.0-85058095958
Institucija/grupa
IHTMTY - JOUR AU - Novaković, Miroslav AU - Đorđević, Iris AU - Todorović, Nina AU - Trifunovic, S. AU - Anđelković, Boban D. AU - Mandić, Boris AU - Jadranin, Milka AU - Vučković, Ivan AU - Vajs, Vlatka AU - Milosavljević, Slobodan AU - Tešević, Vele PY - 2018 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/2389 AB - New aurone epoxide, 2,10-oxy-10-methoxysulfuretin (14), and new auronolignan (15), named cotinignan A, were isolated by silica gel column and semipreparative HPLC chromatography from the methylene chloride/methanol extract of Cotinus coggygria Scop. heartwood. In addition, thirteen known secondary metabolites namely sulfuretin, 2,3-trans-fustin, fisetin, butin, butein, taxifolin, eriodictyol, 3',5,5',7–tetrahydroxyflavanone, 3',4',7-trihydroxyflavone, 3-O-methyl-2,3-trans-fustin, 3-O-galloyl-2,3-trans-fustin, β-resorcylic acid and 3-O-β-sitosterol glucoside were isolated as well. Their structures were elucidated by 1D and 2D NMR, HR-ESI-MS, IR and UV. Ten out of eleven isolated flavonoids possess 7, 3' and 4' hydroxy groups. These structural features could be considered as chemotaxonomic characteristic of flavonoids from C. coggygria. Cotinignan A (15) represents new subclass of secondary metabolites - auronolignans. (Figure presented.). PB - Taylor and Francis Ltd. T2 - Natural Product Research T1 - New aurone epoxide and auronolignan from the heartwood of Cotinus coggygria Scop VL - 33 IS - 19 SP - 2837 EP - 2844 DO - 10.1080/14786419.2018.1508141 ER -
@article{ author = "Novaković, Miroslav and Đorđević, Iris and Todorović, Nina and Trifunovic, S. and Anđelković, Boban D. and Mandić, Boris and Jadranin, Milka and Vučković, Ivan and Vajs, Vlatka and Milosavljević, Slobodan and Tešević, Vele", year = "2018", abstract = "New aurone epoxide, 2,10-oxy-10-methoxysulfuretin (14), and new auronolignan (15), named cotinignan A, were isolated by silica gel column and semipreparative HPLC chromatography from the methylene chloride/methanol extract of Cotinus coggygria Scop. heartwood. In addition, thirteen known secondary metabolites namely sulfuretin, 2,3-trans-fustin, fisetin, butin, butein, taxifolin, eriodictyol, 3',5,5',7–tetrahydroxyflavanone, 3',4',7-trihydroxyflavone, 3-O-methyl-2,3-trans-fustin, 3-O-galloyl-2,3-trans-fustin, β-resorcylic acid and 3-O-β-sitosterol glucoside were isolated as well. Their structures were elucidated by 1D and 2D NMR, HR-ESI-MS, IR and UV. Ten out of eleven isolated flavonoids possess 7, 3' and 4' hydroxy groups. These structural features could be considered as chemotaxonomic characteristic of flavonoids from C. coggygria. Cotinignan A (15) represents new subclass of secondary metabolites - auronolignans. (Figure presented.).", publisher = "Taylor and Francis Ltd.", journal = "Natural Product Research", title = "New aurone epoxide and auronolignan from the heartwood of Cotinus coggygria Scop", volume = "33", number = "19", pages = "2837-2844", doi = "10.1080/14786419.2018.1508141" }
Novaković, M., Đorđević, I., Todorović, N., Trifunovic, S., Anđelković, B. D., Mandić, B., Jadranin, M., Vučković, I., Vajs, V., Milosavljević, S.,& Tešević, V.. (2018). New aurone epoxide and auronolignan from the heartwood of Cotinus coggygria Scop. in Natural Product Research Taylor and Francis Ltd.., 33(19), 2837-2844. https://doi.org/10.1080/14786419.2018.1508141
Novaković M, Đorđević I, Todorović N, Trifunovic S, Anđelković BD, Mandić B, Jadranin M, Vučković I, Vajs V, Milosavljević S, Tešević V. New aurone epoxide and auronolignan from the heartwood of Cotinus coggygria Scop. in Natural Product Research. 2018;33(19):2837-2844. doi:10.1080/14786419.2018.1508141 .
Novaković, Miroslav, Đorđević, Iris, Todorović, Nina, Trifunovic, S., Anđelković, Boban D., Mandić, Boris, Jadranin, Milka, Vučković, Ivan, Vajs, Vlatka, Milosavljević, Slobodan, Tešević, Vele, "New aurone epoxide and auronolignan from the heartwood of Cotinus coggygria Scop" in Natural Product Research, 33, no. 19 (2018):2837-2844, https://doi.org/10.1080/14786419.2018.1508141 . .