New aurone epoxide and auronolignan from the heartwood of Cotinus coggygria Scop
Само за регистроване кориснике
2018
Аутори
Novaković, MiroslavĐorđević, Iris
Todorović, Nina
Trifunovic, S.
Anđelković, Boban D.
Mandić, Boris
Jadranin, Milka
Vučković, Ivan
Vajs, Vlatka
Milosavljević, Slobodan
Tešević, Vele
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
New aurone epoxide, 2,10-oxy-10-methoxysulfuretin (14), and new auronolignan (15), named cotinignan A, were isolated by silica gel column and semipreparative HPLC chromatography from the methylene chloride/methanol extract of Cotinus coggygria Scop. heartwood. In addition, thirteen known secondary metabolites namely sulfuretin, 2,3-trans-fustin, fisetin, butin, butein, taxifolin, eriodictyol, 3',5,5',7–tetrahydroxyflavanone, 3',4',7-trihydroxyflavone, 3-O-methyl-2,3-trans-fustin, 3-O-galloyl-2,3-trans-fustin, β-resorcylic acid and 3-O-β-sitosterol glucoside were isolated as well. Their structures were elucidated by 1D and 2D NMR, HR-ESI-MS, IR and UV. Ten out of eleven isolated flavonoids possess 7, 3' and 4' hydroxy groups. These structural features could be considered as chemotaxonomic characteristic of flavonoids from C. coggygria. Cotinignan A (15) represents new subclass of secondary metabolites - auronolignans. (Figure presented.).
Кључне речи:
cotinignan A / Cotinus coggygria Scop / flavonoids / NMR / semipreparative HPLCИзвор:
Natural Product Research, 2018, 33, 19, 2837-2844Издавач:
- Taylor and Francis Ltd.
Финансирање / пројекти:
- Биоактивни природни производи самониклих, гајених и јестивих биљака: одређивање структура и активности (RS-MESTD-Basic Research (BR or ON)-172053)
Напомена:
- Supplementary material: https://cer.ihtm.bg.ac.rs/handle/123456789/4447
Повезане информације:
- Повезани садржај
https://cer.ihtm.bg.ac.rs/handle/123456789/4447
DOI: 10.1080/14786419.2018.1508141
ISSN: 1478-6419
PubMed: 30513208
WoS: 000478893800017
Scopus: 2-s2.0-85058095958
Институција/група
IHTMTY - JOUR AU - Novaković, Miroslav AU - Đorđević, Iris AU - Todorović, Nina AU - Trifunovic, S. AU - Anđelković, Boban D. AU - Mandić, Boris AU - Jadranin, Milka AU - Vučković, Ivan AU - Vajs, Vlatka AU - Milosavljević, Slobodan AU - Tešević, Vele PY - 2018 UR - https://cer.ihtm.bg.ac.rs/handle/123456789/2389 AB - New aurone epoxide, 2,10-oxy-10-methoxysulfuretin (14), and new auronolignan (15), named cotinignan A, were isolated by silica gel column and semipreparative HPLC chromatography from the methylene chloride/methanol extract of Cotinus coggygria Scop. heartwood. In addition, thirteen known secondary metabolites namely sulfuretin, 2,3-trans-fustin, fisetin, butin, butein, taxifolin, eriodictyol, 3',5,5',7–tetrahydroxyflavanone, 3',4',7-trihydroxyflavone, 3-O-methyl-2,3-trans-fustin, 3-O-galloyl-2,3-trans-fustin, β-resorcylic acid and 3-O-β-sitosterol glucoside were isolated as well. Their structures were elucidated by 1D and 2D NMR, HR-ESI-MS, IR and UV. Ten out of eleven isolated flavonoids possess 7, 3' and 4' hydroxy groups. These structural features could be considered as chemotaxonomic characteristic of flavonoids from C. coggygria. Cotinignan A (15) represents new subclass of secondary metabolites - auronolignans. (Figure presented.). PB - Taylor and Francis Ltd. T2 - Natural Product Research T1 - New aurone epoxide and auronolignan from the heartwood of Cotinus coggygria Scop VL - 33 IS - 19 SP - 2837 EP - 2844 DO - 10.1080/14786419.2018.1508141 ER -
@article{ author = "Novaković, Miroslav and Đorđević, Iris and Todorović, Nina and Trifunovic, S. and Anđelković, Boban D. and Mandić, Boris and Jadranin, Milka and Vučković, Ivan and Vajs, Vlatka and Milosavljević, Slobodan and Tešević, Vele", year = "2018", abstract = "New aurone epoxide, 2,10-oxy-10-methoxysulfuretin (14), and new auronolignan (15), named cotinignan A, were isolated by silica gel column and semipreparative HPLC chromatography from the methylene chloride/methanol extract of Cotinus coggygria Scop. heartwood. In addition, thirteen known secondary metabolites namely sulfuretin, 2,3-trans-fustin, fisetin, butin, butein, taxifolin, eriodictyol, 3',5,5',7–tetrahydroxyflavanone, 3',4',7-trihydroxyflavone, 3-O-methyl-2,3-trans-fustin, 3-O-galloyl-2,3-trans-fustin, β-resorcylic acid and 3-O-β-sitosterol glucoside were isolated as well. Their structures were elucidated by 1D and 2D NMR, HR-ESI-MS, IR and UV. Ten out of eleven isolated flavonoids possess 7, 3' and 4' hydroxy groups. These structural features could be considered as chemotaxonomic characteristic of flavonoids from C. coggygria. Cotinignan A (15) represents new subclass of secondary metabolites - auronolignans. (Figure presented.).", publisher = "Taylor and Francis Ltd.", journal = "Natural Product Research", title = "New aurone epoxide and auronolignan from the heartwood of Cotinus coggygria Scop", volume = "33", number = "19", pages = "2837-2844", doi = "10.1080/14786419.2018.1508141" }
Novaković, M., Đorđević, I., Todorović, N., Trifunovic, S., Anđelković, B. D., Mandić, B., Jadranin, M., Vučković, I., Vajs, V., Milosavljević, S.,& Tešević, V.. (2018). New aurone epoxide and auronolignan from the heartwood of Cotinus coggygria Scop. in Natural Product Research Taylor and Francis Ltd.., 33(19), 2837-2844. https://doi.org/10.1080/14786419.2018.1508141
Novaković M, Đorđević I, Todorović N, Trifunovic S, Anđelković BD, Mandić B, Jadranin M, Vučković I, Vajs V, Milosavljević S, Tešević V. New aurone epoxide and auronolignan from the heartwood of Cotinus coggygria Scop. in Natural Product Research. 2018;33(19):2837-2844. doi:10.1080/14786419.2018.1508141 .
Novaković, Miroslav, Đorđević, Iris, Todorović, Nina, Trifunovic, S., Anđelković, Boban D., Mandić, Boris, Jadranin, Milka, Vučković, Ivan, Vajs, Vlatka, Milosavljević, Slobodan, Tešević, Vele, "New aurone epoxide and auronolignan from the heartwood of Cotinus coggygria Scop" in Natural Product Research, 33, no. 19 (2018):2837-2844, https://doi.org/10.1080/14786419.2018.1508141 . .